Obesity and metabolic syndrome in infancy and adolescence

The prevalence of obesity is increasing all over the world in the last decades. This is a concerning fact since the excess of body fat, especially abdominal fat, is directly related to the lipidic profile that is altered, to the increase of arterial pressure and hyperinsulinemia. All of these are co...

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Bibliographic Details
Authors: Lacroix de OLIVEIRA, Cecília, de MELLO, Marco Túlio, de Pádua CINTRA, Isa, FISBERG, Mauro
Format: article
Status:Published version
Publication Date:2023
Country:Brasil
Institution:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)
Repository:Revista de Nutrição
Language:Portuguese
OAI Identifier:oai:ojs.periodicos.puc-campinas.edu.br:article/9186
Online Access:https://periodicos.puc-campinas.edu.br/nutricao/article/view/9186
Access Level:Open access
Keyword:obesity
child
adolescent
insulin resistence
hyperlipidemia
hypertension
metabolic syndrome
obesidade
criança
adolescente
resistência à insulina
hiperlipidemia
hipertensão
síndrome metabólica
Description
Summary:The prevalence of obesity is increasing all over the world in the last decades. This is a concerning fact since the excess of body fat, especially abdominal fat, is directly related to the lipidic profile that is altered, to the increase of arterial pressure and hyperinsulinemia. All of these are considered risk factors to the onset of chronic-degenerative diseases such as type 2 diabetes and cardiovascular disease. High levels of leptin and the alterations of fibrinolytic factors have also been observed in obese individuals. These modifications are described as “metabolic syndrome” or “insulin resistance syndrome”, since hyperinsulinemia has an important role in the development of other components of the metabolic syndrome. However, the question is if these alterationsare already present in these children and adolescents. This paper describes the physiopathology of the metabolic syndrome components and aims at clarifying how this process takes place in youth.