Two cases of neural tube defects with dolutegravir use at conception in south Brazil
Dolutegravir (DTG) is amongst the most prescribed antiretrovirals worldwide and is recommended as first line regimen in most HIV treatment guidelines. Its use, although infrequently, had been associated to an increased chance of neural tube defects (NTD) in Botswana, Africa. Herein we describe two c...
| Autores: | , , |
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| Tipo de documento: | artigo |
| Estado: | Versão publicada |
| Data de publicação: | 2021 |
| País: | Brasil |
| Recursos: | Universidade Federal do Rio Grande do Sul (UFRGS) |
| Repositório: | Repositório Institucional da UFRGS |
| Idioma: | inglês |
| OAI Identifier: | oai:www.lume.ufrgs.br:10183/236731 |
| Acesso em linha: | http://hdl.handle.net/10183/236731 |
| Access Level: | Acceso aberto |
| Palavra-chave: | HIV Gravidez Defeitos do tubo neural Porto Alegre (RS) COVID-19 Neural tube defects Pregnancy Dolutegravir |
| Resumo: | Dolutegravir (DTG) is amongst the most prescribed antiretrovirals worldwide and is recommended as first line regimen in most HIV treatment guidelines. Its use, although infrequently, had been associated to an increased chance of neural tube defects (NTD) in Botswana, Africa. Herein we describe two cases of NTD in women who conceived while taking DTG as part of their antiretroviral treatment in the city of Porto Alegre, Brazil. |
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