Appearance of anti-acetylcholine receptor antibodies after COVID-19
Objectives: In this paper, we report a case of Myasthenia Gravis (MG) exacerbated by COVID-19 that was initially anti-acetylcholine receptor (AChR) negative and after 9 months became positive for anti-AChR antibodies. Methods: We performed a review of the medical records and clinical follow-up of a...
| Autores: | , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2025 |
| País: | Brasil |
| Institución: | Universidade Federal do Ceará (UFC) |
| Repositorio: | Revista de Medicina da UFC |
| Idioma: | portugués |
| OAI Identifier: | oai:periodicos.ufc:article/90635 |
| Acceso en línea: | https://periodicos.ufc.br/revistademedicinadaufc/article/view/90635 |
| Access Level: | acceso abierto |
| Palabra clave: | Myasthenia Gravis COVID-19 SARS-CoV-2 |
| Sumario: | Objectives: In this paper, we report a case of Myasthenia Gravis (MG) exacerbated by COVID-19 that was initially anti-acetylcholine receptor (AChR) negative and after 9 months became positive for anti-AChR antibodies. Methods: We performed a review of the medical records and clinical follow-up of a patient followed at the Neurology service of Walter Cantídio University Hospital. Results: A 37-year-old female patient presented with mild dysphonia, ptosis and diplopia. Three months later, she was admitted to the hospital with respiratory failure associated with COVID-19. The patient received a clinical diagnosis of MG and anti-AChR and MuSK antibodies were negative at that moment. Nine months after initial presentation, serum anti-AChR antibodies were positive. Conclusion: We reported a patient who presented seroconversion for anti-AChR antibodies after COVID-19. There have been some reports of possible viral triggers for myasthenia, but controversy over this matter still remains. |
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