Trends in prevalence, mortality, and morbidity associated with high systolic blood pressure in Brazil from 1990 to 2017 : estimates from the “Global Burden of Disease 2017” (GBD 2017) study

Nascimento, Bruno Ramos; Brant, Luisa Campos Caldeira; Yadgir, Simon; Oliveira, Glaucia Maria Moraes de; Roth, Gregory A.; Glenn, Scott Devon; Mooney, Meghan D.; Naghavi, Mohsen; Passos, Valéria Maria de Azeredo; Duncan, Bruce Bartholow; Silva, Diego Augusto Santos; Malta, Deborah Carvalho; Ribeiro, Antônio Luiz Pinho

Trends in prevalence, mortality, and morbidity associated with high systolic blood pressure in Brazil from 1990 to 2017 : estimates from the “Global Burden of Disease 2017” (GBD 2017) study

Background: Hypertension remains the leading risk factor for cardiovascular disease (CVD) worldwide, and its impact in Brazil should be assessed in order to better address the issue. We aimed to describe trends in prevalence and burden of disease attributable to high systolic blood pressure (HSBP) a...

ver descrição completa

Detalhes bibliográficos
Autores:	Nascimento, Bruno Ramos, Brant, Luisa Campos Caldeira, Yadgir, Simon, Oliveira, Glaucia Maria Moraes de, Roth, Gregory A., Glenn, Scott Devon, Mooney, Meghan D., Naghavi, Mohsen, Passos, Valéria Maria de Azeredo, Duncan, Bruce Bartholow, Silva, Diego Augusto Santos, Malta, Deborah Carvalho, Ribeiro, Antônio Luiz Pinho
Formato:	artículo
Estado:	Versión publicada
Fecha de publicación:	2020
País:	Brasil
Recursos:	Universidade Federal do Rio Grande do Sul (UFRGS)
Repositorio:	Repositório Institucional da UFRGS
Idioma:	inglés
OAI Identifier:	oai:www.lume.ufrgs.br:10183/229320
Acesso em linha:	http://hdl.handle.net/10183/229320
Access Level:	acceso abierto
Palavra-chave:	Carga global da doença Hipertensão Mortalidade Epidemiologia Brasil Global burden of disease Hypertension Morbidity Mortality Epidemiology

id	BR_8a8f9a28ae5d8d3b4c7cd68d2ceb90e2
oai_identifier_str	oai:www.lume.ufrgs.br:10183/229320
network_acronym_str	BR
network_name_str	Brasil
repository_id_str
spelling	2021-09-01T04:25:17Z20201478-7954http://hdl.handle.net/10183/229320001130474Background: Hypertension remains the leading risk factor for cardiovascular disease (CVD) worldwide, and its impact in Brazil should be assessed in order to better address the issue. We aimed to describe trends in prevalence and burden of disease attributable to high systolic blood pressure (HSBP) among Brazilians ≥ 25 years old according to sex and federal units (FU) using the Global Burden of Disease (GBD) 2017 estimates. Methods: We used the comparative risk assessment developed for the GBD study to estimate trends in attributable deaths and disability-adjusted life-years (DALY), by sex, and FU for HSBP from 1990 to 2017. This study included 14 HSBP-outcome pairs. HSBP was defined as ≥ 140 mmHg for prevalence estimates, and a theoretical minimum risk exposure level (TMREL) of 110–115 mmHg was considered for disease burden. We estimated the portion of deaths and DALYs attributed to HSBP. We also explored the drivers of trends in HSBP burden, as well as the correlation between disease burden and sociodemographic development index (SDI). Results: In Brazil, the prevalence of HSBP is 18.9% (95% uncertainty intervals [UI] 18.5–19.3%), with an annual 0.4% increase rate, while age-standardized death rates attributable to HSBP decreased from 189.2 (95%UI 168.5–209.2) deaths to 104.8 (95%UI 94.9–114.4) deaths per 100,000 from 1990 to 2017. In spite of that, the total number of deaths attributable to HSBP increased 53.4% and HSBP raised from 3rd to 1st position, as the leading risk factor for deaths during the period. Regarding total DALYs, HSBP raised from 4th in 1990 to 2nd cause in 2017. The main driver of change of HSBP burden is population aging. Across FUs, the reduction in the age-standardized death rates attributable to HSBP correlated with higher SDI. Conclusions: While HSBP prevalence shows an increasing trend, age-standardized death and DALY rates are decreasing in Brazil, probably as results of successful public policies for CVD secondary prevention and control, but suboptimal control of its determinants. Reduction was more significant in FUs with higher SDI, suggesting that the effect of health policies was heterogeneous. Moreover, HSBP has become the main risk factor for death in Brazil, mainly due to population aging.application/pdfengPopulation health metrics. London. Vol. 18, supl 1 (2020), 17, 22 p.Carga global da doençaHipertensãoMortalidadeEpidemiologiaBrasilGlobal burden of diseaseHypertensionMorbidityMortalityEpidemiologyTrends in prevalence, mortality, and morbidity associated with high systolic blood pressure in Brazil from 1990 to 2017 : estimates from the “Global Burden of Disease 2017” (GBD 2017) studyEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSNascimento, Bruno RamosBrant, Luisa Campos CaldeiraYadgir, SimonOliveira, Glaucia Maria Moraes deRoth, Gregory A.Glenn, Scott DevonMooney, Meghan D.Naghavi, MohsenPassos, Valéria Maria de AzeredoDuncan, Bruce BartholowSilva, Diego Augusto SantosMalta, Deborah CarvalhoRibeiro, Antônio Luiz PinhoTEXT001130474.pdf.txt001130474.pdf.txtExtracted Texttext/plain85058http://www.lume.ufrgs.br/bitstream/10183/229320/2/001130474.pdf.txte509e6f525ae48f27175c2e3ddde8ebcMD52ORIGINAL001130474.pdfTexto completo (inglês)application/pdf2594087http://www.lume.ufrgs.br/bitstream/10183/229320/1/001130474.pdfeb27b1f3ce6e3f6b7647e84c02095c2cMD5110183/2293202021-09-19 04:30:01.318158oai:www.lume.ufrgs.br:10183/229320Repositório InstitucionalPUBhttps://lume.ufrgs.br/oai/requestlume@ufrgs.bropendoar:2021-09-19T07:30:01Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv	Trends in prevalence, mortality, and morbidity associated with high systolic blood pressure in Brazil from 1990 to 2017 : estimates from the “Global Burden of Disease 2017” (GBD 2017) study
title	Trends in prevalence, mortality, and morbidity associated with high systolic blood pressure in Brazil from 1990 to 2017 : estimates from the “Global Burden of Disease 2017” (GBD 2017) study
spellingShingle	Trends in prevalence, mortality, and morbidity associated with high systolic blood pressure in Brazil from 1990 to 2017 : estimates from the “Global Burden of Disease 2017” (GBD 2017) study Nascimento, Bruno Ramos Carga global da doença Hipertensão Mortalidade Epidemiologia Brasil Global burden of disease Hypertension Morbidity Mortality Epidemiology
title_short	Trends in prevalence, mortality, and morbidity associated with high systolic blood pressure in Brazil from 1990 to 2017 : estimates from the “Global Burden of Disease 2017” (GBD 2017) study
title_full	Trends in prevalence, mortality, and morbidity associated with high systolic blood pressure in Brazil from 1990 to 2017 : estimates from the “Global Burden of Disease 2017” (GBD 2017) study
title_fullStr	Trends in prevalence, mortality, and morbidity associated with high systolic blood pressure in Brazil from 1990 to 2017 : estimates from the “Global Burden of Disease 2017” (GBD 2017) study
title_full_unstemmed	Trends in prevalence, mortality, and morbidity associated with high systolic blood pressure in Brazil from 1990 to 2017 : estimates from the “Global Burden of Disease 2017” (GBD 2017) study
title_sort	Trends in prevalence, mortality, and morbidity associated with high systolic blood pressure in Brazil from 1990 to 2017 : estimates from the “Global Burden of Disease 2017” (GBD 2017) study
dc.creator.none.fl_str_mv	Nascimento, Bruno Ramos Brant, Luisa Campos Caldeira Yadgir, Simon Oliveira, Glaucia Maria Moraes de Roth, Gregory A. Glenn, Scott Devon Mooney, Meghan D. Naghavi, Mohsen Passos, Valéria Maria de Azeredo Duncan, Bruce Bartholow Silva, Diego Augusto Santos Malta, Deborah Carvalho Ribeiro, Antônio Luiz Pinho
author	Nascimento, Bruno Ramos
author_facet	Nascimento, Bruno Ramos Brant, Luisa Campos Caldeira Yadgir, Simon Oliveira, Glaucia Maria Moraes de Roth, Gregory A. Glenn, Scott Devon Mooney, Meghan D. Naghavi, Mohsen Passos, Valéria Maria de Azeredo Duncan, Bruce Bartholow Silva, Diego Augusto Santos Malta, Deborah Carvalho Ribeiro, Antônio Luiz Pinho
author_role	author
author2	Brant, Luisa Campos Caldeira Yadgir, Simon Oliveira, Glaucia Maria Moraes de Roth, Gregory A. Glenn, Scott Devon Mooney, Meghan D. Naghavi, Mohsen Passos, Valéria Maria de Azeredo Duncan, Bruce Bartholow Silva, Diego Augusto Santos Malta, Deborah Carvalho Ribeiro, Antônio Luiz Pinho
author2_role	author author author author author author author author author author author author
dc.subject.por.fl_str_mv	Carga global da doença Hipertensão Mortalidade Epidemiologia Brasil
topic	Carga global da doença Hipertensão Mortalidade Epidemiologia Brasil Global burden of disease Hypertension Morbidity Mortality Epidemiology
dc.subject.eng.fl_str_mv	Global burden of disease Hypertension Morbidity Mortality Epidemiology
description	Background: Hypertension remains the leading risk factor for cardiovascular disease (CVD) worldwide, and its impact in Brazil should be assessed in order to better address the issue. We aimed to describe trends in prevalence and burden of disease attributable to high systolic blood pressure (HSBP) among Brazilians ≥ 25 years old according to sex and federal units (FU) using the Global Burden of Disease (GBD) 2017 estimates. Methods: We used the comparative risk assessment developed for the GBD study to estimate trends in attributable deaths and disability-adjusted life-years (DALY), by sex, and FU for HSBP from 1990 to 2017. This study included 14 HSBP-outcome pairs. HSBP was defined as ≥ 140 mmHg for prevalence estimates, and a theoretical minimum risk exposure level (TMREL) of 110–115 mmHg was considered for disease burden. We estimated the portion of deaths and DALYs attributed to HSBP. We also explored the drivers of trends in HSBP burden, as well as the correlation between disease burden and sociodemographic development index (SDI). Results: In Brazil, the prevalence of HSBP is 18.9% (95% uncertainty intervals [UI] 18.5–19.3%), with an annual 0.4% increase rate, while age-standardized death rates attributable to HSBP decreased from 189.2 (95%UI 168.5–209.2) deaths to 104.8 (95%UI 94.9–114.4) deaths per 100,000 from 1990 to 2017. In spite of that, the total number of deaths attributable to HSBP increased 53.4% and HSBP raised from 3rd to 1st position, as the leading risk factor for deaths during the period. Regarding total DALYs, HSBP raised from 4th in 1990 to 2nd cause in 2017. The main driver of change of HSBP burden is population aging. Across FUs, the reduction in the age-standardized death rates attributable to HSBP correlated with higher SDI. Conclusions: While HSBP prevalence shows an increasing trend, age-standardized death and DALY rates are decreasing in Brazil, probably as results of successful public policies for CVD secondary prevention and control, but suboptimal control of its determinants. Reduction was more significant in FUs with higher SDI, suggesting that the effect of health policies was heterogeneous. Moreover, HSBP has become the main risk factor for death in Brazil, mainly due to population aging.
publishDate	2020
dc.date.issued.fl_str_mv	2020
dc.date.accessioned.fl_str_mv	2021-09-01T04:25:17Z
dc.type.driver.fl_str_mv	Estrangeiro info:eu-repo/semantics/article
dc.type.status.fl_str_mv	info:eu-repo/semantics/publishedVersion
format	article
status_str	publishedVersion
dc.identifier.uri.fl_str_mv	http://hdl.handle.net/10183/229320
dc.identifier.issn.pt_BR.fl_str_mv	1478-7954
dc.identifier.nrb.pt_BR.fl_str_mv	001130474
identifier_str_mv	1478-7954 001130474
url	http://hdl.handle.net/10183/229320
dc.language.iso.fl_str_mv	eng
language	eng
dc.relation.ispartof.pt_BR.fl_str_mv	Population health metrics. London. Vol. 18, supl 1 (2020), 17, 22 p.
dc.rights.driver.fl_str_mv	info:eu-repo/semantics/openAccess
eu_rights_str_mv	openAccess
dc.format.none.fl_str_mv	application/pdf
dc.source.none.fl_str_mv	reponame:Repositório Institucional da UFRGS instname:Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS
instname_str	Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str	UFRGS
institution	UFRGS
reponame_str	Repositório Institucional da UFRGS
collection	Repositório Institucional da UFRGS
bitstream.url.fl_str_mv	http://www.lume.ufrgs.br/bitstream/10183/229320/2/001130474.pdf.txt http://www.lume.ufrgs.br/bitstream/10183/229320/1/001130474.pdf
bitstream.checksum.fl_str_mv	e509e6f525ae48f27175c2e3ddde8ebc eb27b1f3ce6e3f6b7647e84c02095c2c
bitstream.checksumAlgorithm.fl_str_mv	MD5 MD5
repository.name.fl_str_mv	Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv	lume@ufrgs.br
_version_	1853675878363430912
score	15,300719

Trends in prevalence, mortality, and morbidity associated with high systolic blood pressure in Brazil from 1990 to 2017 : estimates from the “Global Burden of Disease 2017” (GBD 2017) study

Registos relacionados