Incidence of withdrawal syndrome in critically ill children undergoing a protocol for discontinuation of analgesia and sedation in a pediatric intensive care unit in Brasília, DF
Background: Analgesia and sedation administered to critically ill pediatric patients in a Pediatric Intensive Care Unit (PICU) can increase the length of stay, tolerance, and the incidence of withdrawal syndrome (WS). This study aimed to assess the incidence of withdrawal signs in critically ill chi...
| Autores: | , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2025 |
| País: | Brasil |
| Recursos: | Editora JRG |
| Repositorio: | Revista JRG de Estudos Acadêmicos |
| Idioma: | portugués |
| OAI Identifier: | oai:ojs2.revistajrg.com:article/1900 |
| Acesso em linha: | http://revistajrg.com/index.php/jrg/article/view/1900 |
| Access Level: | acceso abierto |
| Palavra-chave: | opioides benzodiazepínicos descontinuação analgesia sedação opioids; benzodiazepines; discontinuation; analgesia; sedation |
| Resumo: | Background: Analgesia and sedation administered to critically ill pediatric patients in a Pediatric Intensive Care Unit (PICU) can increase the length of stay, tolerance, and the incidence of withdrawal syndrome (WS). This study aimed to assess the incidence of withdrawal signs in critically ill children undergoing an analgesia and sedation discontinuation protocol (ASDP) in a PICU at a hospital in Brasília, DF. Methods: This was a prospective cohort study of children admitted to a PICU who underwent the ASDP. Patients aged between 1 month and 14 years, who were on mechanical ventilation and hospitalized for over 72 hours, and using opioids and benzodiazepines, were included. Patients were categorized according to the ASDP into low, moderate, high, and very high-risk groups. Data were collected through interviews with the responsible person at the patient's bedside, the application of the WAT-1 tool, and the review of the patient's electronic medical record. The study was approved by the Research Ethics Committee (CAEE 78210624.7.0000.5553). Results: A total of 28 patients with respiratory diagnoses as the main cause were studied. The patients were classified as low (n = 15, 53.6%), moderate (n = 9, 32.1%), and high (n = 4, 14.3%) risk. The incidence of WS was 35.7% (n = 10), and 4 patients required rescue doses of morphine for symptom relief. Conclusion: The incidence of WS was lower than that reported in the literature, although no statistical difference was found between the groups stratified by risk. |
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