Pulmonary alveolar proteinosis and paraneoplastic syndromes: manifestação paraneoplásica?

Pulmonary alveolar proteinosis (PAP) is a rare condition of unknown etiology. It hasbeen described as the presence of periodic acid-Schiff-positive proteinaceous material(rich in lipids) in the alveoli. Its pathogenesis is believed to consist of an overproductionor surfactant removal defect at the l...

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Detalles Bibliográficos
Autores: Pressi, Alexandre, D. Furtado, André, Chachamovich, Régis, Henn, Lucélia, M. Barreto, Sérgio
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:Brasil
Institución:Universidade Federal do Rio Grande do Sul (UFRGS)
Repositorio:Clinical and Biomedical Research
Idioma:portugués
OAI Identifier:oai:seer.ufrgs.br:article/125272
Acceso en línea:https://seer.ufrgs.br/index.php/hcpa/article/view/125272
Access Level:acceso abierto
Palabra clave:Proteinose alveolar
paraneoplásica
pulmonary alveolar proteinosis
paraneoplastic
Descripción
Sumario:Pulmonary alveolar proteinosis (PAP) is a rare condition of unknown etiology. It hasbeen described as the presence of periodic acid-Schiff-positive proteinaceous material(rich in lipids) in the alveoli. Its pathogenesis is believed to consist of an overproductionor surfactant removal defect at the lung. The association of PAP with respiratorydiseases, silicosis, exposure to aluminium or titanium, and hematological neoplasiashas been reported. Here we report two cases of pulmonary alveolar proteinosis andneoplasm diagnosed at the PulmonaryDepartment at Hospital de Clínicas de PortoAlegre.