Uso potencial dos anticonvulsivantes no tratamento ambulatorial da dependência de álcool

Currently three medications (disulfiram, naltrexone and acamprosate) are approved by the FDA to treat alcohol dependence by the FDA. The classical anticonvulsive drugs are rarely employed as an alternative because of their side effects, but the latest generation of anticonvulsants could be useful. T...

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Detalles Bibliográficos
Autores: Castro, Luís André [UNIFESP], Couzi, Carla [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2006
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:portugués
OAI Identifier:oai:repositorio.unifesp.br:11600/2851
Acceso en línea:http://dx.doi.org/10.1590/S0047-20852006000300007
http://repositorio.unifesp.br/handle/11600/2851
Access Level:acceso abierto
Palabra clave:anticonvulsants
alcoholism
carbamazepine
valproic acid
anticonvulsivantes
alcoolismo
carbamazepina
ácido valpróico
Descripción
Sumario:Currently three medications (disulfiram, naltrexone and acamprosate) are approved by the FDA to treat alcohol dependence by the FDA. The classical anticonvulsive drugs are rarely employed as an alternative because of their side effects, but the latest generation of anticonvulsants could be useful. The anticonvulsants can be a alternative to BZD and other pharmacological treatments in the prevention of complications during the detoxification therapy, because of the absence of addictive properties and a better adverse effects profile than classical anticonvulsant drugs. Anticonvulsants such as carbamazepine, valproic acid, gabapentin and topiramate have shown to be excellent treatment for alcohol withdrawal and for the prevention of alcohol relapse. Although none of these agents have been approved by the FDA yet, there is growing evidence in the literature to support their use.