Fructooligosaccharides (FOS) and hormonal replacement therapy (HRT) by estrogen suppressed bone resorption in the ovariectomized rat

Keywords: Menopause – Ovariectomy – Hormonal Replacement Therapy – Prebiotics – Osteoporosis.

Detalles Bibliográficos
Autores: Cardoso Netto, Claudia, Miyasaka, Celio Kenji
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2009
País:Brasil
Institución:Universidade Federal da Bahia (UFBA)
Repositorio:Repositório Institucional da UFBA
Idioma:portugués
OAI Identifier:oai:repositorio.ufba.br:ri/20567
Acceso en línea:http://repositorio.ufba.br/ri/handle/ri/20567
Access Level:acceso abierto
Palabra clave:Menopausa.
Ovariectomia.
Terapia de reposição hormonal.
Prebióticos.
Osteoporose.
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dc.title.pt_BR.fl_str_mv Fructooligosaccharides (FOS) and hormonal replacement therapy (HRT) by estrogen suppressed bone resorption in the ovariectomized rat
dc.title.alternative.pt_BR.fl_str_mv Revista de Ciências Médicas e Biológicas
title Fructooligosaccharides (FOS) and hormonal replacement therapy (HRT) by estrogen suppressed bone resorption in the ovariectomized rat
spellingShingle Fructooligosaccharides (FOS) and hormonal replacement therapy (HRT) by estrogen suppressed bone resorption in the ovariectomized rat
Cardoso Netto, Claudia
Menopausa.
Ovariectomia.
Terapia de reposição hormonal.
Prebióticos.
Osteoporose.
title_short Fructooligosaccharides (FOS) and hormonal replacement therapy (HRT) by estrogen suppressed bone resorption in the ovariectomized rat
title_full Fructooligosaccharides (FOS) and hormonal replacement therapy (HRT) by estrogen suppressed bone resorption in the ovariectomized rat
title_fullStr Fructooligosaccharides (FOS) and hormonal replacement therapy (HRT) by estrogen suppressed bone resorption in the ovariectomized rat
title_full_unstemmed Fructooligosaccharides (FOS) and hormonal replacement therapy (HRT) by estrogen suppressed bone resorption in the ovariectomized rat
title_sort Fructooligosaccharides (FOS) and hormonal replacement therapy (HRT) by estrogen suppressed bone resorption in the ovariectomized rat
dc.creator.none.fl_str_mv Cardoso Netto, Claudia
Miyasaka, Celio Kenji
Cardoso Netto, Claudia
Miyasaka, Celio Kenji
author Cardoso Netto, Claudia
author_facet Cardoso Netto, Claudia
Miyasaka, Celio Kenji
author_role author
author2 Miyasaka, Celio Kenji
author2_role author
dc.subject.por.fl_str_mv Menopausa.
Ovariectomia.
Terapia de reposição hormonal.
Prebióticos.
Osteoporose.
topic Menopausa.
Ovariectomia.
Terapia de reposição hormonal.
Prebióticos.
Osteoporose.
description Keywords: Menopause – Ovariectomy – Hormonal Replacement Therapy – Prebiotics – Osteoporosis.
publishDate 2009
dc.date.issued.fl_str_mv 2009-01
dc.date.accessioned.fl_str_mv 2016-09-15T17:35:05Z
dc.date.available.fl_str_mv 2016-09-15T17:35:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv CARDOSO NETO, C.; MIYASAKA, C. K. Fructooligosaccharides (FOS) and hormonal replacement therapy (HRT) by estrogen suppressed bone resorption in the ovariectomized rat. R. Ci. méd. biol., Salvador, v.8, n.1, p.33-38, jan./abr. 2009.
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/20567
dc.identifier.issn.none.fl_str_mv 2236-5222
dc.identifier.number.pt_BR.fl_str_mv v.8, n.1
identifier_str_mv CARDOSO NETO, C.; MIYASAKA, C. K. Fructooligosaccharides (FOS) and hormonal replacement therapy (HRT) by estrogen suppressed bone resorption in the ovariectomized rat. R. Ci. méd. biol., Salvador, v.8, n.1, p.33-38, jan./abr. 2009.
2236-5222
v.8, n.1
url http://repositorio.ufba.br/ri/handle/ri/20567
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Instituto de Ciências da Saúde/ Universidade Federal da Bahia
dc.publisher.country.fl_str_mv Brasil
publisher.none.fl_str_mv Instituto de Ciências da Saúde/ Universidade Federal da Bahia
dc.source.pt_BR.fl_str_mv http://www.portalseer.ufba.br/index.php/cmbio/article/view/4373/3197
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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spelling 2016-09-15T17:35:05Z2016-09-15T17:35:05Z2009-01CARDOSO NETO, C.; MIYASAKA, C. K. Fructooligosaccharides (FOS) and hormonal replacement therapy (HRT) by estrogen suppressed bone resorption in the ovariectomized rat. R. Ci. méd. biol., Salvador, v.8, n.1, p.33-38, jan./abr. 2009.2236-5222http://repositorio.ufba.br/ri/handle/ri/20567v.8, n.1Keywords: Menopause – Ovariectomy – Hormonal Replacement Therapy – Prebiotics – Osteoporosis.Abstract: The present investigation aims to compare the effects of fructooligosaccharides (FOS) and the hormonal replacement therapy (HRT) by estrogen on bone metabolism in ovariectomized rats. Three-month-old (276,0±3,4g body weight) Wistar female rats were submitted to an ovariectomy (OVT) procedure and after 30 days, the animals were randomLy assigned (n=10) to treatment groups for 20 days. The animals were treated with FOS (RAFTILOSE® P95) (5g/100g of diet intake/day) through intragastric intubations and/or not with hormonal replacement therapy (HRT) by synthetic β-estradiol (SIGMA/E-4389) (30μg/kg of body weight) daily administrated by subcutaneous injection (G1 = OVT + FOS + HRT; G2 = OVT + FOS + saline; G3 = OVT + water + HRT; G4 = OVT + water + saline). The rats were fed with standard diet contend 1.3 % of Ca and received deionized water ad libitum. The data are expressed as the mean values ± standard error means (SEM) and analyzed by two-way ANOVA Tukey’s post-hoc test (p<0.05). Both treatments alone reduced total alkaline phosphatase activity. The FOS treatment increased the tibiae calcium, but the effect of FOS + HRT was more powerful. Radiodensity analysis supports this result too. In femur biomechanical properties, the proportional limit and resilience of FOS + HRT and FOS animals group suggest an increased effect on the bone capacity in absorbing energy. These results are also observed in the qualitative analysis of the SEM. Prebiotics substances consumption should be introduced for prevention or treatment of osteoporosis.Submitted by ROBERTO PAULO CORREIA DE ARAÚJO (ppgorgsistem@ufba.br) on 2016-09-15T17:35:05Z No. of bitstreams: 1 5_v.8_1.pdf: 157578 bytes, checksum: 722d2a1f0b941fa9bd4268b9e0926233 (MD5)Made available in DSpace on 2016-09-15T17:35:05Z (GMT). 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