Persistent interstitial lung abnormalities in post-covid-19 patients: A case series

A new concept of multisystem disease has emerged as a long-term condition following mild-severe COVID-19 infection. The main symptoms of this affection are breathlessness, chest pain, and fatigue. We present here the clinical case of four COVID-19 patients during hospitalization and 60 days after ho...

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Detalles Bibliográficos
Autores: Lago, Vanessa Carvalho [UNESP], Prudente, Robson Aparecido [UNESP], Luzia, Dayane Araujo [UNESP], Franco, Estefânia Thomé [UNESP], Cezare, Talita Jacon [UNESP], Peralta, Amanda [UNESP], Ferreira, Eloara Vieira M., Albuquerque, André Luis Pereira, Okoshi, Marina Politi [UNESP], Baldi, Bruno Guedes, Tanni, Suzana Erico [UNESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/207736
Acceso en línea:http://dx.doi.org/10.1590/1678-9199-JVATITD-2020-0157
http://hdl.handle.net/11449/207736
Access Level:acceso abierto
Palabra clave:COVID-19
CT scan
Interstitial lung abnormalities
Descripción
Sumario:A new concept of multisystem disease has emerged as a long-term condition following mild-severe COVID-19 infection. The main symptoms of this affection are breathlessness, chest pain, and fatigue. We present here the clinical case of four COVID-19 patients during hospitalization and 60 days after hospital discharge. Physiological impairment of all patients was assessed by spirometry, dyspnea score, arterial blood gas, and 6-minute walk test 60 days after hospital discharge, and computed tomographic scan 90 days after discharge. All patients had fatigue, which was not related to hypoxemia or impaired spirometry values, and interstitial lung alterations, which occurred in both mechanically ventilated and non-mechanically ventilated patients. In conclusion, identifying the prevalence and patterns of permanent lung damage is paramount in preventing and treating COVID-19-induced fibrotic lung disease. Additionally, and based on our preliminary results, it will be also relevant to establish long-term outpatient programs for these individuals.