Interdisciplinarity in HIV prevention research: the experience of the PrEP1519 study protocol among adolescent MSM and TGW in Brazil

At the end of 2017, Brazil adopted HIV pre-exposure prophylaxis (PrEP) as part of a combination prevention strategy for the most at-risk populations. However, Brazil does not have specific guidelines for PrEP use among adolescents aged < 18 years. Therefore, researchers from different health...

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Bibliographic Details
Authors: Dourado, Ines, Magno, Laio, Bartolomeu Greco, Dirceu, Miura Zucchi, Eliana, Aurélia de Souza Ferraz, Dulce, Rodrigues Westin, Mateus, Grangeiro, Alexandre
Format: article
Status:Published version
Publication Date:2023
Country:Brasil
Institution:Fundação Oswaldo Cruz (FIOCRUZ)
Repository:Cadernos de Saúde Pública
Language:English
OAI Identifier:oai:ojs.teste-cadernos.ensp.fiocruz.br:article/8301
Online Access:https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/8301
Access Level:Open access
Keyword:HIV
Profilaxia Pré-Exposição
Adolescentes
Homens que Fazem Sexo com Homens
Mulher Transgênero
VIH
Profilaxis Pre-Exposición
Hombres que Hacen Sexo con Hombres
Mujer Transexual
Pre-Exposure Prophylaxis
Adolescents
Men Who Have Sex With Men
Transgender Women
Description
Summary:At the end of 2017, Brazil adopted HIV pre-exposure prophylaxis (PrEP) as part of a combination prevention strategy for the most at-risk populations. However, Brazil does not have specific guidelines for PrEP use among adolescents aged < 18 years. Therefore, researchers from different health disciplines conducted PrEP1519, the first PrEP demonstration cohort study, ongoing in three Brazilian cities – Salvador, Belo Horizonte, and São Paulo – among adolescent men who have sex with men and transgender women, aged 15-19 years. This study aims to evaluate the effectiveness of PrEP in real-world settings. Quantitative and qualitative methods were integrated to obtain data on PrEP acceptability, uptake, use, and adherence. Moreover, comprehensive services and friendly environments were implemented in the PrEP1519 clinics. This study aims to describe the collaborative efforts of interdisciplinary practices in the development of the PrEP1519 study. The articulation of researchers from different institutions and areas is challenging; but it also allows for a broader outlook on questions regarding the direction of the research, while enriching the decisions needed to be taken during the interactions and negotiations among the different individuals, including the youth team and participants. Furthermore, it reflects on the communication process between cultures and languages considering the trans-epistemic arena of knowledge production about HIV, sexually transmitted infections, PrEP, and other combination prevention strategies for adolescents.