Physical exercise, neuroplasticity, spatial learning and memory

There has long been discussion regarding the positive effects of physical exercise on brain activity. However, physical exercise has only recently begun to receive the attention of the scientific community, with major interest in its effects on the cognitive functions, spatial learning and memory, a...

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Detalles Bibliográficos
Autores: Cassilhas, Ricardo Cardoso [UNIFESP], Tufik, Sergio [UNIFESP], Mello, Marco Tulio de
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2016
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:inglés
OAI Identifier:oai:repositorio.unifesp.br:11600/57944
Acceso en línea:https://dx.doi.org/10.1007/s00018-015-2102-0
https://repositorio.unifesp.br/handle/11600/57944
Access Level:acceso abierto
Palabra clave:Aerobic exercise
Resistance exercise
Neuroplasticity
Brain
Cognition
Memory
Descripción
Sumario:There has long been discussion regarding the positive effects of physical exercise on brain activity. However, physical exercise has only recently begun to receive the attention of the scientific community, with major interest in its effects on the cognitive functions, spatial learning and memory, as a non-drug method of maintaining brain health and treating neurodegenerative and/or psychiatric conditions. In humans, several studies have shown the beneficial effects of aerobic and resistance exercises in adult and geriatric populations. More recently, studies employing animal models have attempted to elucidate the mechanisms underlying neuroplasticity related to physical exercise-induced spatial learning and memory improvement, even under neurodegenerative conditions. In an attempt to clarify these issues, the present review aims to discuss the role of physical exercise in the improvement of spatial learning and memory and the cellular and molecular mechanisms involved in neuroplasticity.