Stabilization of an amylase from Neurospora crassa by Immobilization on Highly Activated Supports

The amylase from Neurospora crassa is an interesting enzyme, having higher stability than amylase from Aspergillus oryzea under a broad range of pH values. Moreover, the N. crassa enzyme may be immobilized on different supports with good retention of enzyme activity. The best stabilizations were ach...

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Detalles Bibliográficos
Autores: Tavano, Olga L., Pessela, Benevides C. C., Goulart, Antonio J., Fernández-Lafuente, Roberto, Guisán, José M., Monti, Rubens [UNESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2008
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/225248
Acceso en línea:http://dx.doi.org/10.1080/08905430802262616
http://hdl.handle.net/11449/225248
Access Level:acceso abierto
Palabra clave:Amylase
Enzyme immobilization
Enzyme stabilization
Glyoxyl agarose
Neurospora crassa
Descripción
Sumario:The amylase from Neurospora crassa is an interesting enzyme, having higher stability than amylase from Aspergillus oryzea under a broad range of pH values. Moreover, the N. crassa enzyme may be immobilized on different supports with good retention of enzyme activity. The best stabilizations were achieved using Eupergit C 250 L or glyoxyl agarose, with which the enzyme remained fully active at 60°C for 24 h while the soluble enzyme remained about 17%. The glyoxyl agarose immobilized enzyme had high thermostability, high optimal temperature (65°C) and broad pH/activity profile, suggesting that this enzyme has potential for food and industrial applications for starch modification. Copyright © Taylor & Francis Group, LLC.