Avaliação de fatores clínicos, laboratoriais e ultrassonográficos preditores de malignidade em nódulos tiroidianos

OBJECTIVE: To evaluate the risk of malignancy in thyroid nodules through clinical, laboratory, ultrasonographic and cytological aspects. PATIENTS AND METHODS: 741 nodules of 407 patients. RESULTS: The cytology was benign (60,5%), indeterminate (23,3%), malignant (8,3%) or nondiagnostic (7,6%). The p...

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Detalles Bibliográficos
Autores: Rio, Ana Luiza Silva [UNIFESP], Biscolla, Rosa Paula Mello [UNIFESP], Andreoni, Danielle Macellaro [UNIFESP], Camacho, Cléber Pinto [UNIFESP], Nakabashi, Cláudia Cristina Doimo [UNIFESP], Mamone, Maria da Conceição de Oliveira Carneiro [UNIFESP], Ikejiri, Elza Setsuku [UNIFESP], Matsumura, Luiza Kimiko [UNIFESP], Hidal, Jairo Tabacow [UNIFESP], Maciel, Rui Monteiro de Barros [UNIFESP], Furlanetto, Reinaldo Perrone [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2011
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:portugués
OAI Identifier:oai:repositorio.unifesp.br:11600/6308
Acceso en línea:http://dx.doi.org/10.1590/S0004-27302011000100004
http://repositorio.unifesp.br/handle/11600/6308
Access Level:acceso abierto
Palabra clave:Thyroid nodules
male sex
age
ultrasonography
fine needle aspiration biopsy
Nódulo de tiroide
sexo masculino
idade
ultrassonografia
punção de tiroide
Descripción
Sumario:OBJECTIVE: To evaluate the risk of malignancy in thyroid nodules through clinical, laboratory, ultrasonographic and cytological aspects. PATIENTS AND METHODS: 741 nodules of 407 patients. RESULTS: The cytology was benign (60,5%), indeterminate (23,3%), malignant (8,3%) or nondiagnostic (7,6%). The prevalence of cancer in indeterminate citology was 18,5% (16% in follicular lesions, 44% in suspicious). The diagnosis of malignancy was 17,2% (n = 70). The frequency of cancer in women (15,2%) was lower than in men (27,9%). There was an inverse relation between age and cancer risk. There was no statistical significance in the prevalence of cancer according to number, size of nodules or TSH levels. Hypoechogenicity and microcalcifications on ultrasound were risk factors. CONCLUSION: The risk of malignancy was higher in men, hypoechoic nodules, with microcalcifications and was inversely related to age. The TSH level was not an independent factor predictive of malignancy.

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