Bactericidal and Bioactive Ceramic Scaffold

Infections caused by bacteria are among the main factors for the rejection of materials used in implants. Ceramic scaffolds containing silver have been shown to be bioactive and bactericidal for different strains of bacteria. In this work, glasses containing silver were synthesized by the sol-gel me...

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Detalles Bibliográficos
Autores: Dias de Oliveira, Camila Dias de Oliveira, de Campos, Gabrieli Andressa, Cheleski Wiggers , Juliana, de Campos, Elvio Antônio, Denofre de Campos, Silvia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:Brasil
Institución:Universidade Federal de Mato Grosso do Sul (UFMS)
Repositorio:Orbital - The Electronic Journal of Chemistry (Campo Grande)
Idioma:inglés
OAI Identifier:oai:periodicos.ufms.br:article/20255
Acceso en línea:https://periodicos.ufms.br/index.php/orbital/article/view/20255
Access Level:acceso abierto
Palabra clave:antibacterial, bioglass scaffolds, hydroxyapatite, silver nanoparticle
Descripción
Sumario:Infections caused by bacteria are among the main factors for the rejection of materials used in implants. Ceramic scaffolds containing silver have been shown to be bioactive and bactericidal for different strains of bacteria. In this work, glasses containing silver were synthesized by the sol-gel method to obtain scaffolds. Bands were observed in the 1200–930 cm-1 region that can be attributed to Si–O–Si bonds, but also bands of overlapping phosphate groups, bands at 490 cm-1 of Si–O–NBO, Si–O-Zn, and diffraction peaks corresponding to the hydroxyapatite phase. Bioactivity tests in the presence of the body fluid simulating solution (SBF) and antibacterial activity tests indicate that the glass and scaffolds are bioactive and bactericidal.