GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virus

GloPID-R chikungunya, o'nyong-nyong and Mayaro virus Working Group.

Detalles Bibliográficos
Autores: Pezzi, L., Labeaud, A. D., Reusken, C. B., Drexler, Jan Felix, Vasilakis, N., Diallo, M., Simon, F., Jaenisch, T., Gallian, P., Sall, A., Failloux, A. B., Weaver, S. C., Lamballerie, X. de, Boyer, S., Brasil, Patrícia, Busch, M., Diamond, M. S., Drebot, M. A., Kohl, A., Lecuit, M., Oliveira, Ricardo Lourenço de, Neytsy, J., Ng, Lfp, Ribeiro, Guilherme de Sousa, Rios, M., Rodriguez-Morales, A. J., Freitas, Maria Goreti Rosa, Simmons, G., Siqueira, André Machado de, Rua, A. Vega
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:Brasil
Institución:Fundação Oswaldo Cruz (FIOCRUZ)
Repositorio:Repositório Institucional da FIOCRUZ (ARCA)
Idioma:inglés
OAI Identifier:oai:arca.fiocruz.br:icict/36851
Acceso en línea:https://arca.fiocruz.br/handle/icict/36851
Access Level:acceso abierto
Palabra clave:Vírus Chikungunya
O'nyong-nyong Virus
História Natural das Doenças
Soroprevalência
Epidemiologia
Chikungunya virus
Natural History of Diseases
Soroprevalence
Epidemiology
03 Saúde e Bem-Estar
id BR_71c61b76d7dbf4e2cbcb65e8e822d0fc
oai_identifier_str oai:arca.fiocruz.br:icict/36851
network_acronym_str BR
network_name_str Brasil
repository_id_str
dc.title.none.fl_str_mv GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virus
title GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virus
spellingShingle GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virus
Pezzi, L.
Vírus Chikungunya
O'nyong-nyong Virus
História Natural das Doenças
Soroprevalência
Epidemiologia
Chikungunya virus
O'nyong-nyong Virus
Natural History of Diseases
Soroprevalence
Epidemiology
03 Saúde e Bem-Estar
title_short GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virus
title_full GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virus
title_fullStr GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virus
title_full_unstemmed GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virus
title_sort GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virus
dc.creator.none.fl_str_mv Pezzi, L.
Labeaud, A. D.
Reusken, C. B.
Drexler, Jan Felix
Vasilakis, N.
Diallo, M.
Simon, F.
Jaenisch, T.
Gallian, P.
Sall, A.
Failloux, A. B.
Weaver, S. C.
Lamballerie, X. de
Boyer, S.
Brasil, Patrícia
Busch, M.
Diamond, M. S.
Drebot, M. A.
Kohl, A.
Lecuit, M.
Oliveira, Ricardo Lourenço de
Neytsy, J.
Ng, Lfp
Ribeiro, Guilherme de Sousa
Rios, M.
Rodriguez-Morales, A. J.
Freitas, Maria Goreti Rosa
Simmons, G.
Siqueira, André Machado de
Rua, A. Vega
author Pezzi, L.
author_facet Pezzi, L.
Labeaud, A. D.
Reusken, C. B.
Drexler, Jan Felix
Vasilakis, N.
Diallo, M.
Simon, F.
Jaenisch, T.
Gallian, P.
Sall, A.
Failloux, A. B.
Weaver, S. C.
Lamballerie, X. de
Boyer, S.
Brasil, Patrícia
Busch, M.
Diamond, M. S.
Drebot, M. A.
Kohl, A.
Lecuit, M.
Oliveira, Ricardo Lourenço de
Neytsy, J.
Ng, Lfp
Ribeiro, Guilherme de Sousa
Rios, M.
Rodriguez-Morales, A. J.
Freitas, Maria Goreti Rosa
Simmons, G.
Siqueira, André Machado de
Rua, A. Vega
author_role author
author2 Labeaud, A. D.
Reusken, C. B.
Drexler, Jan Felix
Vasilakis, N.
Diallo, M.
Simon, F.
Jaenisch, T.
Gallian, P.
Sall, A.
Failloux, A. B.
Weaver, S. C.
Lamballerie, X. de
Boyer, S.
Brasil, Patrícia
Busch, M.
Diamond, M. S.
Drebot, M. A.
Kohl, A.
Lecuit, M.
Oliveira, Ricardo Lourenço de
Neytsy, J.
Ng, Lfp
Ribeiro, Guilherme de Sousa
Rios, M.
Rodriguez-Morales, A. J.
Freitas, Maria Goreti Rosa
Simmons, G.
Siqueira, André Machado de
Rua, A. Vega
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.other.none.fl_str_mv Vírus Chikungunya
O'nyong-nyong Virus
História Natural das Doenças
Soroprevalência
Epidemiologia
topic Vírus Chikungunya
O'nyong-nyong Virus
História Natural das Doenças
Soroprevalência
Epidemiologia
Chikungunya virus
O'nyong-nyong Virus
Natural History of Diseases
Soroprevalence
Epidemiology
03 Saúde e Bem-Estar
dc.subject.en.none.fl_str_mv Chikungunya virus
O'nyong-nyong Virus
Natural History of Diseases
Soroprevalence
Epidemiology
dc.subject.ods.none.fl_str_mv 03 Saúde e Bem-Estar
description GloPID-R chikungunya, o'nyong-nyong and Mayaro virus Working Group.
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-11-04T18:31:10Z
dc.date.available.fl_str_mv 2019-11-04T18:31:10Z
dc.date.issued.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv PEZZI, L. et al. GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virus. Antiviral Research, v. 172, p. 1-8, Dec. 2019.
dc.identifier.uri.fl_str_mv https://arca.fiocruz.br/handle/icict/36851
dc.identifier.issn.none.fl_str_mv 0166-3542
dc.identifier.doi.none.fl_str_mv 10.1016/j.antiviral.2019.104611
dc.identifier.eissn.none.fl_str_mv 1872-9096
identifier_str_mv PEZZI, L. et al. GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virus. Antiviral Research, v. 172, p. 1-8, Dec. 2019.
0166-3542
10.1016/j.antiviral.2019.104611
1872-9096
url https://arca.fiocruz.br/handle/icict/36851
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://arca.fiocruz.br/bitstreams/2970264a-c174-4b45-8631-ef3ac52967c7/download
https://arca.fiocruz.br/bitstreams/2089da73-3186-4774-b805-bacf39fe37d4/download
https://arca.fiocruz.br/bitstreams/84caf361-4600-494e-bf46-0eb1dbbb8155/download
https://arca.fiocruz.br/bitstreams/e11a54fb-62dd-4510-801d-784447dbd6d8/download
bitstream.checksum.fl_str_mv 5a560609d32a3863062d77ff32785d58
a18956ecb6df7ba2c79ca5451ad67cb3
202ae0ed4d9d9ea9a82dc360d74fe808
1869f421f31482b8cf6b342bc302c544
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1853674415464644608
spelling 2019-11-04T18:31:10Z2019-11-04T18:31:10Z2019PEZZI, L. et al. GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virus. Antiviral Research, v. 172, p. 1-8, Dec. 2019.0166-3542https://arca.fiocruz.br/handle/icict/3685110.1016/j.antiviral.2019.1046111872-9096GloPID-R chikungunya, o'nyong-nyong and Mayaro virus Working Group.Aix-Marseille Université. Unité des Virus Émergents. Marseille, France / Université de Corse-Inserm. Laboratoire de Virologie. Corte, France.Stanford University. School of Medicine. Division of Infectious Diseases. Department of Pediatrics. Palo Alto, CA, USA.National Institute for Public Health and the Environment. Centre for Infectious Disease Control. Bilthoven, The Netherlands / Erasmus University Medical Center. Department Viroscience. Rotterdam, The Netherlands.Humboldt-Universität zu Berlin. Corporate Member of Freie Universität Berlin. Charité-Universitätsmedizin Berlin. Berlin, Germany / Berlin Institute of Health. Institute of Virology. Berlin, Germany / German Centre for Infection Research. Germany.University of Texas. Medical Branch. Institute of Human Infection and Immunity. Department of Pathology. Galveston, TX, USA.Institut Pasteur de Dakar. Unité D'Entomologie Médicale. Dakar, Senegal.Laveran Military Teaching Hospital. Marseille, France.Heidelberg University Hospital. Department of Infectious Diseases. Section Clinical Tropical Medicine. Heidelberg, Germany.Établissement Français Du Sang Alpes Méditerranée. Marseille, France.Institut Pasteur de Dakar. Unité D'Entomologie Médicale. Dakar, Senegal.Institut Pasteur. Department of Virology. Arboviruses and Insect Vectors Unit. Paris, France.University of Texas Medical Branch. Institute for Human Infections and Immunity. Department of Microbiology and Immunology. Galveston, TX, USA.Aix-Marseille Université. Unité des Virus Émergents. Marseille, France.Institut Pasteur Du Cambodge. Medical Entomology Platform. Phnom Penh, Cambodia.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Blood Systems Research Institute. San Francisco, CA, USA / University of California. Department of Laboratory Medicine. San Francisco, CA, USA.Washington University. School of Medicine. Department of Medicine. Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs. St. Louis, MO, USA / Washington University. School of Medicine. Department of Molecular Microbiology. Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs. St. Louis, MO, USA / Washington University. School of Medicine. Department of Pathology and Immunology. Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs. St. Louis, MO, USA.Public Health Agency of Canada. National Microbiology Laboratory. Zoonotic Diseases and Special Pathogens. Winnipeg, Canada.Medical Research Council. University of Glasgow. Centre for Virus Research. Glasgow, UK.Institut Pasteur. Biology of Infection Unit. Inserm U1117. Paris Descartes University. Departement of Infectious Diseases and Tropical Medicine. Necker-Enfants Malades University Hospital. APHP. IHU Imagine. Paris, France.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Mosquitos Transmissores de Hematozoários. Rio de Janeiro, RJ, Brasil.Katholieke Universiteit Leuven. Rega Institute for Medical Research. Department of Microbiology and Immunology. Laboratory of Virology and Chemotherapy. Leuven, Belgium.Singapore Immunology Network. Agency for Science, Technology and Research (A*STAR). Singapore.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Salvador, BA, Brasil.U.S. Food and Drug Administration. Center for Biologics Evaluation and Research. Office of Blood Research and Review. Division of Emerging and Transfusion Transmitted Diseases. Laboratory of Emerging Pathogens. Silver Spring, MD, USA.Universidad Tecnologica de Pereira. Faculty of Health Sciences. Public Health and Infection Research Group. Pereira, Colombia.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Mosquitos Transmissores de Hematozoários. Rio de Janeiro, RJ, Brasil.Aix-Marseille Université. Unité des Virus Émergents. Marseille, France / National Institute for Public Health and the Environment. Centre for Infectious Disease Control. Bilthoven, The Netherlands.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Aix-Marseille Université. Unité des Virus Émergents. Marseille, France / Erasmus University Medical Center. Department Viroscience. Rotterdam, The Netherlands.The GloPID-R (Global Research Collaboration for Infectious Disease Preparedness) chikungunya (CHIKV), o'nyong-nyong (ONNV) and Mayaro virus (MAYV) Working Group has been established to identify gaps of knowledge about the natural history, epidemiology and medical management of infection by these viruses, and to provide adapted recommendations for future investigations. Here, we present a report dedicated to ONNV epidemiological distribution. Two large-scale ONNV outbreaks have been identified in Africa in the last 60 years, interspersed with sporadic serosurveys and case reports of returning travelers. The assessment of the real scale of ONNV circulation in Africa remains a difficult task and surveillance studies are necessary to fill this gap. The identification of ONNV etiology is made complicated by the absence of multiplex tools in co-circulation areas and that of reference standards, as well as the high cross-reactivity with related pathogens observed in serological tests, in particular with CHIKV. This is a specific obstacle for seroprevalence studies, that necessitate an improvement of serological tools to provide robust results. The scarcity of existent genetic data currently limits molecular epidemiology studies. ONNV epidemiology would also benefit from reinforced entomological and environmental surveillance. Finally, the natural history of the disease deserves to be further investigated, with a specific attention paid to long-term complications. Considering our incomplete knowledge on ONNV distribution, GloPID-R CHIKV, ONNV and MAYV experts recommend that a major effort should be done to fill existing gaps.engElsevierVírus ChikungunyaO'nyong-nyong VirusHistória Natural das DoençasSoroprevalênciaEpidemiologiaChikungunya virusO'nyong-nyong VirusNatural History of DiseasesSoroprevalenceEpidemiology03 Saúde e Bem-EstarGloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virusinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZPezzi, L.Labeaud, A. D.Reusken, C. B.Drexler, Jan FelixVasilakis, N.Diallo, M.Simon, F.Jaenisch, T.Gallian, P.Sall, A.Failloux, A. B.Weaver, S. C.Lamballerie, X. deBoyer, S.Brasil, PatríciaBusch, M.Diamond, M. S.Drebot, M. A.Kohl, A.Lecuit, M.Oliveira, Ricardo Lourenço deNeytsy, J.Ng, LfpRibeiro, Guilherme de SousaRios, M.Rodriguez-Morales, A. J.Freitas, Maria Goreti RosaSimmons, G.Siqueira, André Machado deRua, A. VegaLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://arca.fiocruz.br/bitstreams/2970264a-c174-4b45-8631-ef3ac52967c7/download5a560609d32a3863062d77ff32785d58MD51falseAnonymousREADORIGINALPezzi, I GloPID-R part 2.pdfPezzi, I GloPID-R part 2.pdfapplication/pdf926493https://arca.fiocruz.br/bitstreams/2089da73-3186-4774-b805-bacf39fe37d4/downloada18956ecb6df7ba2c79ca5451ad67cb3MD52trueAnonymousREADTEXTPezzi, I GloPID-R part 2.pdf.txtPezzi, I GloPID-R part 2.pdf.txtExtracted texttext/plain43342https://arca.fiocruz.br/bitstreams/84caf361-4600-494e-bf46-0eb1dbbb8155/download202ae0ed4d9d9ea9a82dc360d74fe808MD513falseAnonymousREADTHUMBNAILPezzi, I GloPID-R part 2.pdf.jpgPezzi, I GloPID-R part 2.pdf.jpgGenerated Thumbnailimage/jpeg36945https://arca.fiocruz.br/bitstreams/e11a54fb-62dd-4510-801d-784447dbd6d8/download1869f421f31482b8cf6b342bc302c544MD514falseAnonymousREADicict/368512025-12-10 13:01:59.887open.accessoai:arca.fiocruz.br:icict/36851https://arca.fiocruz.brRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352025-12-10T16:01:59Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)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
score 15,301603

Similares en LA Referencia