Implementation of a New Experimental Animal Model - Zebrafish

Danio rerio (zebrafish, paulistinha) is a freshwater small fish that has been used as an animal model for studies of several human diseases. Its characteristics of being easily bred and reproduced and its laboratory housing methods are well established. It requires some basic care and the acquisitio...

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Detalles Bibliográficos
Autores: Schneider, Ana Cláudia Reis, Maurer, Rafael Lucyk, Matte, Ursula, Porawski, Marilene, Schaefer, Pedro Guilherme, dos Santos, Jorge Luiz, da Silveira, Themis Reverbel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2009
País:Brasil
Institución:Universidade Federal do Rio Grande do Sul (UFRGS)
Repositorio:Clinical and Biomedical Research
Idioma:portugués
OAI Identifier:oai:seer.ufrgs.br:article/7981
Acceso en línea:https://seer.ufrgs.br/index.php/hcpa/article/view/7981
Access Level:acceso abierto
Palabra clave:Zebrafish
Danio rerio
Modelo Animal
Zebrafisch
danio rerio
Descripción
Sumario:Danio rerio (zebrafish, paulistinha) is a freshwater small fish that has been used as an animal model for studies of several human diseases. Its characteristics of being easily bred and reproduced and its laboratory housing methods are well established. It requires some basic care and the acquisition of specific low-cost equipment. Since this fish has already been considered a good human disease model, it may serve as a powerful preclinical platform for the study of molecular events, therapeutic strategies, and for evaluating the physiological mechanisms of some pathologies. The Laboratory of Experimental Hepatology and Gastroenterology (LEHG) of the Research Center of Hospital de Clínicas de Porto Alegre initiated studies with the zebrafish in 2008, presented here.