Eficácia da suplementação de ferro associado ou não à vitamina A no controle da anemia em escolares
This study aimed to evaluate the efficacy of weekly iron supplementation with or without vitamin A in the treatment of iron deficiency anemia, using an experimental, randomized, non-placebo-controlled design in 1999. 267 schoolchildren 6 to 14 years of age were randomized to two treatment groups: on...
| Authors: | , , , , |
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| Format: | article |
| Status: | Published version |
| Publication Date: | 2007 |
| Country: | Brasil |
| Institution: | Fundação Oswaldo Cruz (FIOCRUZ) |
| Repository: | Cadernos de Saúde Pública |
| Language: | Portuguese |
| OAI Identifier: | oai:ojs.teste-cadernos.ensp.fiocruz.br:article/3042 |
| Online Access: | https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3042 |
| Access Level: | Open access |
| Keyword: | Anemia Ferropriva Vitamina A Sulfato Ferroso Estudantes |
| Summary: | This study aimed to evaluate the efficacy of weekly iron supplementation with or without vitamin A in the treatment of iron deficiency anemia, using an experimental, randomized, non-placebo-controlled design in 1999. 267 schoolchildren 6 to 14 years of age were randomized to two treatment groups: one group (144) received 200mg iron sulfate alone, with 40mg of elemental iron, while the other (123) received the same iron supplementation dose plus 10,000 IU of vitamin A (both groups for 30 weeks). Final anemia prevalence was reduced from 48.4% to 17.7% (p < 0.001) in the group receiving iron supplementation alone and 58.1% to 14.3% (p < 0.001) in the group receiving iron plus vitamin A. There was no significant difference between the groups at the end of the study according to mean Hb (p = 0.355) and anemia (p = 0.479). There was a significant correction for iron deficiency anemia with weekly iron-alone supplementation, but with no additional advantage of vitamin A. New studies on the synergism between these two micronutrients are recommended. |
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