HLA in Brazilian Ashkenazic Jews with chronic dermatophytosis caused by Trichophyton rubrum

The frequency of HLA (Human Leucocyte Antigens) was analyzed in 25 non-consanguineous Brazilian Ashkenazic Jews, resident in the city of São Paulo, Brazil, suffering from chronic dermatophytosis caused by T. rubrum, and in 25 non-infected individuals belonging to the same ethnic group. Statistically...

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Detalles Bibliográficos
Autores: Sadahiro, Aya, Feresin Moraes, José Roberto, Hue Moraes, Maria Elisa, Romero, Matilde, Lima Gouvea, Nancy Alves de, Gouvea, Celso José, Ogusku, Maurício Morishi, Campbell, Iphis Tenfuss, Zaitz, Clarisse
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2004
País:Brasil
Institución:Instituto Nacional de Pesquisas da Amazônia (INPA)
Repositorio:Repositório Institucional do INPA
Idioma:inglés
OAI Identifier:oai:repositorio:1/16396
Acceso en línea:https://repositorio.inpa.gov.br/handle/1/16396
Access Level:acceso abierto
Palabra clave:Trichophyton Rubrum
Descripción
Sumario:The frequency of HLA (Human Leucocyte Antigens) was analyzed in 25 non-consanguineous Brazilian Ashkenazic Jews, resident in the city of São Paulo, Brazil, suffering from chronic dermatophytosis caused by T. rubrum, and in 25 non-infected individuals belonging to the same ethnic group. Statistically significant values (p<0.05) were observed for HLA-B14 associated with resistance to chronic dermatophytosis and HLA-DQB1*06 (p=0.05) possibly related to susceptibility. These findings suggest that genes on the chromosome 6, in the region of the major histocompatibility complex, may influence the development of chronic dermatophytosis.