Verrucous hemangioma and histopathological differential diagnosis with angiokeratoma circumscriptum neviforme

Verrucous hemangioma is a rare vascular skin disorder with an immune profile similar to vascular neoplasms, but with behavior and evolution of vascular malformations. Its main differential diagnosis is angiokeratoma circumscriptum neviforme, with an almost indistinguishable clinical presentation bec...

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Detalles Bibliográficos
Autores: Oppermann, Kenselyn, Boff, Ana Letícia, Bonamigo, Renan Rangel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:Brasil
Institución:Universidade Federal do Rio Grande do Sul (UFRGS)
Repositorio:Repositório Institucional da UFRGS
Idioma:inglés
OAI Identifier:oai:www.lume.ufrgs.br:10183/184267
Acceso en línea:http://hdl.handle.net/10183/184267
Access Level:acceso abierto
Palabra clave:Hemangioma
Angioceratoma
Neoplasias cutâneas
Diagnóstico diferencial
Pré-escolar
Angiokeratoma
Skin diseases
Vascular
Descripción
Sumario:Verrucous hemangioma is a rare vascular skin disorder with an immune profile similar to vascular neoplasms, but with behavior and evolution of vascular malformations. Its main differential diagnosis is angiokeratoma circumscriptum neviforme, with an almost indistinguishable clinical presentation because both diseases appear as erythematous patches that evolve to violaceous plaques, becoming scaly and even verrucous, most commonly affecting the lower limbs. Histopathology is crucial for the correct diagnosis: while in angiokeratoma the vascular alterations are limited to the papillary dermis, verrucous hemangioma extends deep into the dermis, reaching the subcutaneous tissue.