Eficácia da avaliação audiométrica no tratamento medicamentoso da otospongiose

Otospongiosis is a primary osteodystrophy of the otic capsule that affects genetically predisposed individuals and leads to a progressive hearing loss. AIM: To evaluate the applicability of audiometric evaluation during drug treatment for otospongiosis. MATERIALS AND METHODS: A prospective, randomiz...

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Detalhes bibliográficos
Autores: Vicente, Andy de Oliveira, Yamashita, Helio Kiitiro [UNIFESP], Cruz, Oswaldo Laércio Mendonça [UNIFESP], Suzuki, Flavia Alencar de Barros [UNIFESP], Penido, Norma de Oliveira [UNIFESP]
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:Brasil
Recursos:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:portugués
OAI Identifier:oai:repositorio.unifesp.br:11600/7081
Acesso em linha:http://dx.doi.org/10.1590/S1808-86942012000200012
http://repositorio.unifesp.br/handle/11600/7081
Access Level:acceso abierto
Palavra-chave:audiometry
hearing loss
otosclerosis
audiometria
otosclerose
perda auditiva
Descrição
Resumo:Otospongiosis is a primary osteodystrophy of the otic capsule that affects genetically predisposed individuals and leads to a progressive hearing loss. AIM: To evaluate the applicability of audiometric evaluation during drug treatment for otospongiosis. MATERIALS AND METHODS: A prospective, randomized, controlled, double-blind study involving 26 patients with clinical, audiometric and CT scan image of otosclerosis. Patients eligible for the study were divided into three groups (A, B and C) and received treatment with alendronate sodium (B), sodium fluoride (C) and placebo (A) for 6 months. After this period they were submitted to new tests. RESULTS: There were not statistically significant differences between air and bone conduction (gap). We also found no differences in the speech recognition threshold (SRT) and speech discrimination (IRF) between before and after treatment. CONCLUSION: After six months of drug treatment the audiometric evaluation kept the same hearing thresholds, suggesting stabilization of the otospongiotic lesions.