B-type natriuretic peptide in the evaluation of cardiac function

B type natriuretic peptide (BNP) and its precursor, the inactive form of NT-pro-BNP, are currently the most studied laboratory parameters in the heart disease spectrum. The assessment of their blood concentrations provides invaluable information on the likelihood, severity and prognosis of the disea...

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Detalhes bibliográficos
Autores: Valle,Adriana Polachini do, Villas Boas,Paulo José Fortes, Vidal,Edison Iglesias de Oliveira, Fukushima,Fernanda Bono
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2013
País:Brasil
Recursos:Sociedade Brasileira de Patologia (SBP)
Repositório:Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
Idioma:inglês
OAI Identifier:oai:scielo:S1676-24442013000400002
Acesso em linha:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000400002
Access Level:Acceso aberto
Palavra-chave:B-type natriuretic peptide
cardiac function
Descrição
Resumo:B type natriuretic peptide (BNP) and its precursor, the inactive form of NT-pro-BNP, are currently the most studied laboratory parameters in the heart disease spectrum. The assessment of their blood concentrations provides invaluable information on the likelihood, severity and prognosis of the disease. The present review aims to describe the biological determinants, the factors that influence these peptide concentrations, the suggested cutoff values for the diagnosis of heart failure and the use of this biomarker in the assessment of cardiac function.