Seroprevalence of cytomegalovirus and its coinfection with epstein-barr virus in adult residents from manaus: A population-based study

Introduction: This study assessed the seroprevalence of cytomegalovirus, associated factors, and Epstein-Barr virus coinfection among adult residents of Manaus. Methods: Using a cross-sectional study design, we collected blood samples from 136 individuals in a household survey in 2016. Prevalence ra...

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Bibliographic Details
Authors: Tiguman, Gustavo Magno Baldin, Poll, Laura Beatrice, Alves, Carlos Eduardo de Castro, Pontes, Gemilson Soares, Silva, Marcus Tolentino, Galvão, Taís Freire
Format: article
Status:Published version
Publication Date:2020
Country:Brasil
Institution:Instituto Nacional de Pesquisas da Amazônia (INPA)
Repository:Repositório Institucional do INPA
Language:English
OAI Identifier:oai:repositorio:1/15145
Online Access:https://repositorio.inpa.gov.br/handle/1/15145
Access Level:Open access
Keyword:Virus Antibody
Adolescent
Adult
Blood
Brasil
Cross-sectional Study
Cytomegalovirus
Cytomegalovirus Infection
Epstein Barr Virus
Epstein Barr Virus Infection
Female
Human
Immunology
Male
Middle Aged
Mixed Infection
Prevalence
Risk Factor
Seroepidemiology
Socioeconomics
Young Adult
Antibodies, Viral
Coinfection
Cross-sectional Studies
Cytomegalovirus Infections
Epstein-barr Virus Infections
Herpesvirus 4, Human
Humans
Risk Factors
Seroepidemiologic Studies
Socioeconomic Factors
Description
Summary:Introduction: This study assessed the seroprevalence of cytomegalovirus, associated factors, and Epstein-Barr virus coinfection among adult residents of Manaus. Methods: Using a cross-sectional study design, we collected blood samples from 136 individuals in a household survey in 2016. Prevalence ratios were calculated using Poisson regression. Results: Cytomegalovirus and Epstein-Barr virus seroprevalences were 67.6% (95% CI: 9.7-75.6%) and 97.8% (95% CI: 95.3-100.0%), respectively. Coinfection was observed in 66.2% (95% CI: 58.1-74.2%) of participants. Bivariate analysis showed no statistical association. Conclusions: Seroprevalences were high among participants and approximately 7 out of 10 individuals had cytomegalovirus and Epstein-Barr virus coinfection. © 2020, Sociedade Brasileira de Medicina Tropical. All rights reserved.

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