Oral mucosal hyperpigmentation caused by lingering use of antimalarial drug

Some pharmacological therapies can be responsible for the appearance of discolorations in the oral mucosal membrane. The antimalarial agents are frequently related to the hiperpigmentation and to their immunesupressive and anti-inflammatory activity. These pharmacological agents are used in the trea...

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Detalles Bibliográficos
Autores: Dias da Silveira, Heloísa Emília, Francisco de Quadros, Onofre, Dal Moro Maito, Fabio Luiz, Giordani, Suiane
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2003
País:Brasil
Institución:Universidade Federal do Rio Grande do Sul (UFRGS)
Repositorio:Revista da Faculdade de Odontologia de Porto Alegre (Online)
Idioma:portugués
OAI Identifier:oai:seer.ufrgs.br:article/103204
Acceso en línea:https://seer.ufrgs.br/index.php/RevistadaFaculdadeOdontologia/article/view/103204
Access Level:acceso abierto
Palabra clave:Pigmentation
Chloroquine
Antimalarials
Pigmentação
Cloroquina
Antimaláricos
Descripción
Sumario:Some pharmacological therapies can be responsible for the appearance of discolorations in the oral mucosal membrane. The antimalarial agents are frequently related to the hiperpigmentation and to their immunesupressive and anti-inflammatory activity. These pharmacological agents are used in the treatment of immunologically mediated conditions. The authors present two cases of pigmentation by antimalarial agent (chloroquine) in oral mucosal membrane of hard palate, emphasizing the need of the dental surgeon to familiarize with these hiperpigmentations in order to facilitate the differential diagnosis with several alterations that promote discolorations in the oral mucosal.