Incidência de neutropenia induzida por quimioterapia no tratamento do câncer colorretal

Objective: to analyze the incidence of neutropenia in patients with colorectal cancer, undergoing chemotherapy treatment. Methods: integrative review performed in the following databases: National Library of Medicine, National Institutes of Health, Cumulative Index to Nursing and Allied Health Liter...

Descripción completa

Detalles Bibliográficos
Autores: Barbosa, Rafael Fernando Mendes, Toneti, Bruna Francielle, Avelar, uliana Maria de Paula aviera, Baviera, Amanda Fonseca, Okino, Liyoko, Sawada, Namie Okino
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:Brasil
Institución:Universidade Federal do Ceará (UFC)
Repositorio:Repositório Institucional da Universidade Federal do Ceará (UFC)
Idioma:portugués
OAI Identifier:oai:repositorio.ufc.br:riufc/40570
Acceso en línea:http://www.repositorio.ufc.br/handle/riufc/40570
Access Level:acceso abierto
Palabra clave:Neutropenia
Neoplasias Colorretais
Protocolos de Quimioterapia Combinada Antineoplásica
Incidência
Descripción
Sumario:Objective: to analyze the incidence of neutropenia in patients with colorectal cancer, undergoing chemotherapy treatment. Methods: integrative review performed in the following databases: National Library of Medicine, National Institutes of Health, Cumulative Index to Nursing and Allied Health Literature, Latin American literature and Caribbean Center in Health Sciences, and SciVerse Scopus. Results: 499 articles were identified, of which 15 met the criteria for inclusion, published between 2006 and 2016 and analyzed in their entirety. Neutropenia was the most reported hematologic toxicity in 12 (80.0%) studies, and the second most common in three (20.0%), in varying degrees, being responsible for reducing and/or delaying of doses in six (40.0%) studies. Conclusion: the studies included in this review showed that neutropenia in patients with colorectal cancer in chemotherapy treatment have low incidences in different degrees, despite the significantly high rates of neutropenia associations, as the most common adverse event in the various analyzed regimes.