Response of the periapical tissue of dogs' teeth to the action of citric acid and EDTA

The purpose of this study was to analyze the inflammatory response of dog's periapical tissues to 17% trisodium EDTA salt (pH 8.0) and 1% citric acid (pH 2.0). Saline was used as a control. Six adult dogs were used as the biological model of the study. The experimental units comprised 56 roots...

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Autores: Sperandio, Cristina Berthold, Silveira, Luiz Fernando Machado, Araújo, Lenita Aver de, Martos, Josué, Malshe, Ashwin
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2008
País:Brasil
Institución:Universidade de São Paulo (USP)
Repositorio:Journal of applied oral science (Online)
Idioma:inglés
OAI Identifier:oai:revistas.usp.br:article/3539
Acceso en línea:https://www.revistas.usp.br/jaos/article/view/3539
Access Level:acceso abierto
Palabra clave:Citric acid
Ethylenediaminetetraacetic acid
Biocompatibility
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spelling Response of the periapical tissue of dogs' teeth to the action of citric acid and EDTA Citric acidEthylenediaminetetraacetic acidBiocompatibility The purpose of this study was to analyze the inflammatory response of dog's periapical tissues to 17% trisodium EDTA salt (pH 8.0) and 1% citric acid (pH 2.0). Saline was used as a control. Six adult dogs were used as the biological model of the study. The experimental units comprised 56 roots of mandibular molars (first and second) and premolars (first, second and third). After coronal opening, pulpectomy and root canal instrumentation were performed using the above-mentioned irrigating solutions. After 24 and 48 hours, the animals were euthanized and the teeth and their supporting tissues were removed and histologically processed. The sections were stained with hematoxylin and eosin and analyzed histopathologically with a light microscope at x100 magnification. The histological analysis focused on the occurrence of acute inflammatory response. The presence of swelling, vasodilatation and inflammatory cells were evaluated and the degree of inflammation was determined for each case. Data were analyzed by Fisher's exact test using the SPSS software with a confidence interval of 95% (pUniversidade de São Paulo. Faculdade de Odontologia de Bauru2008-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/353910.1590/S1678-77572008000100012Journal of Applied Oral Science; Vol. 16 No. 1 (2008); 59-63 Journal of Applied Oral Science; Vol. 16 Núm. 1 (2008); 59-63 Journal of Applied Oral Science; v. 16 n. 1 (2008); 59-63 1678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/3539/4229Copyright (c) 2008 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessSperandio, Cristina BertholdSilveira, Luiz Fernando MachadoAraújo, Lenita Aver deMartos, JosuéMalshe, Ashwin2012-04-27T11:59:57Zoai:revistas.usp.br:article/3539Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2012-04-27T11:59:57Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Response of the periapical tissue of dogs' teeth to the action of citric acid and EDTA
title Response of the periapical tissue of dogs' teeth to the action of citric acid and EDTA
spellingShingle Response of the periapical tissue of dogs' teeth to the action of citric acid and EDTA
Sperandio, Cristina Berthold
Citric acid
Ethylenediaminetetraacetic acid
Biocompatibility
title_short Response of the periapical tissue of dogs' teeth to the action of citric acid and EDTA
title_full Response of the periapical tissue of dogs' teeth to the action of citric acid and EDTA
title_fullStr Response of the periapical tissue of dogs' teeth to the action of citric acid and EDTA
title_full_unstemmed Response of the periapical tissue of dogs' teeth to the action of citric acid and EDTA
title_sort Response of the periapical tissue of dogs' teeth to the action of citric acid and EDTA
dc.creator.none.fl_str_mv Sperandio, Cristina Berthold
Silveira, Luiz Fernando Machado
Araújo, Lenita Aver de
Martos, Josué
Malshe, Ashwin
author Sperandio, Cristina Berthold
author_facet Sperandio, Cristina Berthold
Silveira, Luiz Fernando Machado
Araújo, Lenita Aver de
Martos, Josué
Malshe, Ashwin
author_role author
author2 Silveira, Luiz Fernando Machado
Araújo, Lenita Aver de
Martos, Josué
Malshe, Ashwin
author2_role author
author
author
author
dc.subject.por.fl_str_mv Citric acid
Ethylenediaminetetraacetic acid
Biocompatibility
topic Citric acid
Ethylenediaminetetraacetic acid
Biocompatibility
description The purpose of this study was to analyze the inflammatory response of dog's periapical tissues to 17% trisodium EDTA salt (pH 8.0) and 1% citric acid (pH 2.0). Saline was used as a control. Six adult dogs were used as the biological model of the study. The experimental units comprised 56 roots of mandibular molars (first and second) and premolars (first, second and third). After coronal opening, pulpectomy and root canal instrumentation were performed using the above-mentioned irrigating solutions. After 24 and 48 hours, the animals were euthanized and the teeth and their supporting tissues were removed and histologically processed. The sections were stained with hematoxylin and eosin and analyzed histopathologically with a light microscope at x100 magnification. The histological analysis focused on the occurrence of acute inflammatory response. The presence of swelling, vasodilatation and inflammatory cells were evaluated and the degree of inflammation was determined for each case. Data were analyzed by Fisher's exact test using the SPSS software with a confidence interval of 95% (p
publishDate 2008
dc.date.none.fl_str_mv 2008-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3539
10.1590/S1678-77572008000100012
url https://www.revistas.usp.br/jaos/article/view/3539
identifier_str_mv 10.1590/S1678-77572008000100012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3539/4229
dc.rights.driver.fl_str_mv Copyright (c) 2008 Journal of Applied Oral Science
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2008 Journal of Applied Oral Science
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
dc.source.none.fl_str_mv Journal of Applied Oral Science; Vol. 16 No. 1 (2008); 59-63
Journal of Applied Oral Science; Vol. 16 Núm. 1 (2008); 59-63
Journal of Applied Oral Science; v. 16 n. 1 (2008); 59-63
1678-7765
1678-7757
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
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