Introgression of natural genetic variations affecting trichome development and terpenes biosynthesis to obtain insect-resistant tomatoes

To deal with insect pests the tomato wild relatives produce a variety of defensive compounds in their glandular trichomes type-VI. By contrast, although cultivated tomatoes (Solanum lycopersicum L.), also display type-VI trichomes, the gland in cultivated tomato is much smaller containing mainly mon...

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Detalhes bibliográficos
Autor: Freitas, Rodrigo Therezan de
Formato: tesis doctoral
Estado:Versión publicada
Fecha de publicación:2019
País:Brasil
Recursos:Universidade de São Paulo (USP)
Repositorio:Biblioteca Digital de Teses e Dissertações da USP
Idioma:inglés
OAI Identifier:oai:teses.usp.br:tde-22012020-165551
Acesso em linha:http://www.teses.usp.br/teses/disponiveis/11/11144/tde-22012020-165551/
Access Level:acceso abierto
Palavra-chave:Glandular trichomes
Insect resistance
Introgression line
Linhagem de introgressão
Resistência à inseto
Sesquiterpenes
Sesquiterpeno
Tomate
Tomato
Tricoma glandular
Descrição
Resumo:To deal with insect pests the tomato wild relatives produce a variety of defensive compounds in their glandular trichomes type-VI. By contrast, although cultivated tomatoes (Solanum lycopersicum L.), also display type-VI trichomes, the gland in cultivated tomato is much smaller containing mainly monoterpenes and low levels of cytosolic-derived sesquiterpenes, which have no apparent effect against insect pests. In the present work, we carried out crosses between the wild species S. habrochaites and the tomato cultivar Micro-Tom (MT) in order to create introgression lines (ILs). We successfully transferred the plastid-derived sesquiterpene pathway from S. habrochaites to type-VI trichomes of the cultivated tomato (cv. Micro-Tom). The trichomes of the introgressed line named MT-Sesquiterpene synthase 2 (MT-Sst2) showed even higher concentration of &#945;<span lang=EN-US>-santalene, &#946;<span lang=EN-US>-bergamotene, and &#945;<span lang=EN-US>-bergamotene compared to the wild species type-VI glandular trichomes. Surprisingly, the presence of high amounts of plastid-derived sesquiterpenes was not sufficient to confer resistance to specific tomato pests in MT-Sst2. The sesquiterpene profile of MT-Sst2 and LA1777 unveils sesquiterpene-derived compounds only found in the wild species, which point for additional steps necessary to obtain insect-resistant tomatoes. This work paves the way for both the understanding of the morphology and functionality of type-VI trichomes and for breeding insect resistant tomatoes.