Otimizando o componente farmacológico da terapia integrada da vertigem
Drug treatment is an important option for the treatment of peripheral vestibular diseases. AIM: To identify the drug component associated with optimal integrated balance therapy (IBT) for Ménière s disease or other peripheral vestibular disorders. MATERIALS AND METHODS: Analysis of a series of patie...
| Autores: | , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2007 |
| País: | Brasil |
| Institución: | Universidade Federal de São Paulo (UNIFESP) |
| Repositorio: | Repositório Institucional da UNIFESP |
| Idioma: | portugués |
| OAI Identifier: | oai:repositorio.unifesp.br:11600/3514 |
| Acceso en línea: | http://dx.doi.org/10.1590/S0034-72992007000100003 http://repositorio.unifesp.br/handle/11600/3514 |
| Access Level: | acceso abierto |
| Palabra clave: | meniere s disease labyrinth diseases dizziness vertigo doença de ménière doenças do labirinto tontura vertigem |
| Sumario: | Drug treatment is an important option for the treatment of peripheral vestibular diseases. AIM: To identify the drug component associated with optimal integrated balance therapy (IBT) for Ménière s disease or other peripheral vestibular disorders. MATERIALS AND METHODS: Analysis of a series of patients with Ménière s disease patients or patients with other peripheral vestibular disorders that received IBT involving either no medication or betahistine, cinnarizine, clonazepam, flunarizine or Ginkgo biloba during 120 days. RESULTS: In Ménière s disease, significant differences were observed for all drug therapies (60 days) versus no medication; betahistine was significantly more effective than all other drugs at 60 and 120 days. For non-Ménière s disorders, significant differences were observed among betahistine, cinnarizine, clonazepam and flunarizine and no medication after 60 days; all drug therapies were significantly more effective than no medication after 120 days; betahistine, cinnarizine or clonazepam were equally effective and betahistine was more effective than flunarizine and EGb 761. All treatment options were well tolerated. CONCLUSIONS: Drug therapies were more effective than no medication in the IBT for patients with Ménière s disease or other peripheral vestibular disorders. Betahistine was the most effective medication for patients with Ménière s disease and was as effective as cinnarizine and clonazepam for other peripheral vestibular disorders. |
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