Efeito do choque hipovolêmico na anastomose do intestino delgado de ratos
Objective Study the effect of hypovolemic shock on small intestinal anastomose in adult rats. Method Ninety male rats were randomly divided into five groups: standard, hypovolemic shock, anastomose alone, hypovolemic shock + anastomose and hypovolemic shock + anastomose + blood reinfusion. Hypovolem...
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2001 |
| País: | Brasil |
| Institución: | Universidade Federal de São Paulo (UNIFESP) |
| Repositorio: | Repositório Institucional da UNIFESP |
| Idioma: | portugués |
| OAI Identifier: | oai:repositorio.unifesp.br:11600/1136 |
| Acceso en línea: | http://dx.doi.org/10.1590/S0004-28032001000200007 http://repositorio.unifesp.br/handle/11600/1136 |
| Access Level: | acceso abierto |
| Palabra clave: | Shock Anastomosis, surgical Intestine, small Rats Choque Anastomose cirúrgica Intestino delgado Ratos |
| Sumario: | Objective Study the effect of hypovolemic shock on small intestinal anastomose in adult rats. Method Ninety male rats were randomly divided into five groups: standard, hypovolemic shock, anastomose alone, hypovolemic shock + anastomose and hypovolemic shock + anastomose + blood reinfusion. Hypovolemic shock was achieved by bleeding 30% of the blood volume of the animal. A single layer extramucosal intestinal anastomose was performed. Following intestinal anastomose, the blood volume was restored in group shock, anastomose and blood reinfusion, using heparinized autologous. Results and Conclusion In the experimental model used, hypovolemic shock provoked histological lesions to the mucosa and increased colagen fiber deposition into the submucosa in the region of intestinal anastomose which were progressive with post-operative period. In addition, when the hypovolemic shock group were pressure tested there was a tendency towards a weakening of the intestinal wall at day 7 which became more evident at day 21 as compared to the control groups. |
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