Lactone derivatives produced by a Phaeoacremonium sp., an endophytic fungus from Senna spectabilis

Three new isoaigialones, A, B, and C (1–3), along with aigialone (4), were isolated from the crude EtOAc extract of a Phaeoacremonium sp., an endophytic fungus obtained from the leaves of Senna spectabilis. The structures of these compounds were elucidated based on the analysis of spectroscopic data...

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Detalhes bibliográficos
Autores: Silva, Geraldo H., Zeraik, Maria L., Oliveira, Camila M. de, Teles, Helder L., Trevisan, Henrique C., Pfenning, Ludwig H., Nicolli, Camila P., Young, Maria C. M., Mascarenhas, Yvonne P., Abreu, Lucas M., Saraiva, Amanda C., Medeiros, Alexandra I., Bolzani, Vanderlan da S., Araujo, Angela R.
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:Brasil
Recursos:Universidade Federal de Viçosa (UFV)
Repositorio:LOCUS Repositório Institucional da UFV
Idioma:inglés
OAI Identifier:oai:locus.ufv.br:123456789/19907
Acesso em linha:https://doi.org/10.1021/acs.jnatprod.5b00828
http://www.locus.ufv.br/handle/123456789/19907
Access Level:acceso abierto
Palavra-chave:Phaeoacremonium sp.
Senna spectabilis
Descrição
Resumo:Three new isoaigialones, A, B, and C (1–3), along with aigialone (4), were isolated from the crude EtOAc extract of a Phaeoacremonium sp., an endophytic fungus obtained from the leaves of Senna spectabilis. The structures of these compounds were elucidated based on the analysis of spectroscopic data. Compounds 2 and 4 were active against the phytopathogenic fungi Cladosporium cladosporioides and C. sphaerospermum. This is the first report of metabolites produced by an Phaeoacremonium sp., associated with S. spectabilis.