Interferência do hematócrito sobre o desempenho de dois glicosímetros veterinários em cães

Glucometers (GT) are widely used as tools for monitoring blood glucose in dogs and hematocrit (HT) is one of the factors that can change its accuracy, possibly due to the change in blood viscosity, preventing the reaction with plasma on the surface of the strip, alteration of the diffusion kinetics...

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Detalles Bibliográficos
Autores: Fernanda Morcatti Coura, Maria Correa Lopes, Fabiola de Oliveira Paes Leme, Adriane Pimenta da Costa-Val
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:Brasil
Institución:Universidade Federal de Minas Gerais (UFMG)
Repositorio:Repositório Institucional da UFMG
Idioma:portugués
OAI Identifier:oai:repositorio.ufmg.br:1843/67436
Acceso en línea:https://doi.org/10.15361/2175-0106.2020v36n1p47-51
http://hdl.handle.net/1843/67436
https://orcid.org/0000-0003-2243-3125
https://orcid.org/0000-0002-4013-0147
Access Level:acceso abierto
Palabra clave:Cães
Glicemia
Monitoramento
Glicemia - medição
Descripción
Sumario:Glucometers (GT) are widely used as tools for monitoring blood glucose in dogs and hematocrit (HT) is one of the factors that can change its accuracy, possibly due to the change in blood viscosity, preventing the reaction with plasma on the surface of the strip, alteration of the diffusion kinetics and / or modification of the plasma volume, resulting in insufficient plasma volume for the GT test. This study evaluated the effect of HT on the performance of two veterinary GT for use in dogs compared to two reference laboratory methods (MLab): glucose hexokinase (Hx) and glucose oxidase (GOx). Both GT showed good performance in samples with HT below 37%: GT1 r = 0.90 with MLab Hx and r = 0.94 for GOx. In turn, GT2 presented r = 0.84 for both Hx and GOx. However, only GT1 demonstrated adequate performance in samples with HT between 37% and 55% (r = 0.90 for Hx) and no GT offered adequate performance in samples with HT greater than 55%. It can be concluded that the result presented by both GT changes according to the animal's hematocrit. It should be considered that patients with dysglycemias are frequently exposed to clinical-pathological changes, and the adoption of these specific GT as a monitoring strategy may not be adequate, so the importance of other procedures glucose measurement devices are employed.