Nutrional status and dietary factors in cystic fibrosis patients with delta F508 mutation
ObjectiveTo examine the association between nutritional status and dietary factors in children and adolescents with cystic fibrosis that are carriers of delta F508 mutation. MethodsCross-sectional study of cystic fibrosis children and adolescents. Nutritional status (body mass index percentile) and...
| Autores: | , |
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| Tipo de documento: | artigo |
| Estado: | Versão publicada |
| Data de publicação: | 2023 |
| País: | Brasil |
| Recursos: | Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS) |
| Repositório: | Revista de Nutrição |
| Idioma: | inglês |
| OAI Identifier: | oai:ojs.periodicos.puc-campinas.edu.br:article/8233 |
| Acesso em linha: | https://periodicos.puc-campinas.edu.br/nutricao/article/view/8233 |
| Access Level: | Acceso aberto |
| Palavra-chave: | Cystic fibrosis Diet Nutritional status Fibrose cística Dieta Estado nutricional |
| Resumo: | ObjectiveTo examine the association between nutritional status and dietary factors in children and adolescents with cystic fibrosis that are carriers of delta F508 mutation. MethodsCross-sectional study of cystic fibrosis children and adolescents. Nutritional status (body mass index percentile) and dietary intake (3-day diet records presented as a percentage of estimated energy requirement) were assessed. ResultsThirty six patients (median of 8.6; interquartile range 6.8-12.5 years; 50% male). The Poisson regression analysis showed that the carriers for delta F508 mutation had 60% lower prevalence ratio of body mass index ≥25° (PR=0.4; 95%IC=0.2-0.8) and 90% lower prevalence ratio (PR=0.1; confidence interval 95%IC=0.02-0.3) of ≥150% of estimated energy requirement when compared with non-delta F508 mutation carriers. The model was adjusted for lung function, estimated energy requirement, and body mass index. ConclusionCarriers for delta F508 mutation showed lower body mass index percentile and lower daily caloric consumption when compared with patients without this mutation. |
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