Comparing dextrose prolotherapy with other substances in knee osteoarthritis pain relief: A systematic review

The objective of this study is to compare the effectiveness of dextrose-prolotherapy with other substances for pain relief in patients with primary knee osteoarthritis. The literature screening was done in January 2021 through Medline (PubMed), EMBASE, and Database of the National Institute of Healt...

ver descrição completa

Detalhes bibliográficos
Autores: Cortez, Vitor Santos, Moraes, Walter Augusto, Taba, João Victor, Condi, Alberto, Suzuki, Milena Oliveira, Nascimento, Fernanda Sayuri do, Pipek, Leonardo Zumerkorn, Mattos, Vitoria Carneiro de, Torsani, Matheus Belloni, Meyer, Alberto, Hsing, Wu Tu, Iuamoto, Leandro Ryuchi
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:Brasil
Recursos:Universidade de São Paulo (USP)
Repositorio:Clinics
Idioma:inglés
OAI Identifier:oai:revistas.usp.br:article/213598
Acesso em linha:https://www.revistas.usp.br/clinics/article/view/213598
Access Level:acceso abierto
Palavra-chave:Prolotherapy
Dextrose
Knee
Osteoarthritis
Pain
Descrição
Resumo:The objective of this study is to compare the effectiveness of dextrose-prolotherapy with other substances for pain relief in patients with primary knee osteoarthritis. The literature screening was done in January 2021 through Medline (PubMed), EMBASE, and Database of the National Institute of Health based on the following criteria: randomized clinical trials that subjected patients with primary knee osteoarthritis who underwent treatment with dextrose-prolotherapy and other substances for pain relief. Paired reviewers independently identified 3381 articles and included 8 trials that met the eligibility criteria. According to the findings of this review, participants that underwent dextrose-prolotherapy showed improvements between baseline and posterior assessments and when compared to saline injections, but when compared to other substances, the results were not clear. Although dextrose-prolotherapy is a useful treatment method by itself, it is still not possible to clearly affirm that it is superior or inferior to its counterparts. There is an urgent need for further studies to bring more evidence to the field.

Registos relacionados