Transplante de células-tronco epiteliais límbicas alógenas expandidas ex vivo sobre membrana amniótica: relato de caso

Case report of a patient who developed failure of an allogenic living related conjunctival limbal transplantation in the right eye after an episode of epidemic keratoconjunctivitis. After a few months, she underwent transplantation of allogenic limbal epithelial stem cells cultivated ex vivo on amni...

Descripción completa

Detalles Bibliográficos
Autores: Gomes, José Álvaro Pereira [UNIFESP], Pazos, Henrique Santiago Baltar, Silva, André Berger Emiliano, Cristovam, Priscila Cardoso [UNIFESP], Belfort, Rubens Junior [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2009
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:portugués
OAI Identifier:oai:repositorio.unifesp.br:11600/4978
Acceso en línea:http://dx.doi.org/10.1590/S0004-27492009000200025
http://repositorio.unifesp.br/handle/11600/4978
Access Level:acceso abierto
Palabra clave:Epithelium, corneal
Limbus corneae
Stem cells transplantation
Amnion
Case reports
Epitélio anterior
Limbo da córnea
Transplante de células-tronco
Âmnio
Relatos de casos
Descripción
Sumario:Case report of a patient who developed failure of an allogenic living related conjunctival limbal transplantation in the right eye after an episode of epidemic keratoconjunctivitis. After a few months, she underwent transplantation of allogenic limbal epithelial stem cells cultivated ex vivo on amniotic membrane (first case in Brazil). The patient evolved with total corneal epithelialization and improvement of the visual acuity. Three months after the surgery, peripheral superficial neovascularization with worsening of the corneal transparency was observed. The vision remained 0.1 after one year of the transplantation.