Ventilatory demand during stepping and running: implications for Exercise-Induced Bronchoconstriction in children

BACKGROUND: Single-step tests have been proposed as simple and inexpensive challenges todiagnose exercise-induced bronchoconstriction (EIB) in the pediatric population. Work performed and the resulting ventilation, however, might be substantially lower in stepping than running. This might decrease t...

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Detalles Bibliográficos
Autores: Jessyca Pachi Rodrigues Selman, Fernanda de Cordoba Lanza, Gustavo Falbo Wandalsen, Dirceu Solé, Denis O'Donnell, José Alberto Neder, Simone Dal Corso
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:Brasil
Institución:Universidade Federal de Minas Gerais (UFMG)
Repositorio:Repositório Institucional da UFMG
Idioma:inglés
OAI Identifier:oai:repositorio.ufmg.br:1843/40070
Acceso en línea:https://doi.org/10.4187/respcare.09881
http://hdl.handle.net/1843/40070
http://orcid.org/0000-0002-4748-6947
https://orcid.org/ 0000-0002-8019-281X
https://orcid.org/ 0000-0001-9190-6796
https://orcid.org/0000-0001-9182-7385
Access Level:acceso abierto
Palabra clave:Exercise
Ventilation
Asthma
Dyspnea
Exercise-induced asthma
Children
Exercícios respiratórios
Ventilação pulmonar
Asma
Asma induzida por exercício
Crianças
Descripción
Sumario:BACKGROUND: Single-step tests have been proposed as simple and inexpensive challenges todiagnose exercise-induced bronchoconstriction (EIB) in the pediatric population. Work performed and the resulting ventilation, however, might be substantially lower in stepping than running. This might decrease the diagnostic yield of step-based challenges. METHODS: In a cross-sectional study, 53 children with asthma with exercise-related symptoms (34 boys, age 6–18 y) underwent an incremental stepping test, a 6-min constant stepping test, and a treadmill running test on different days. RESULTS: Constant and incremental stepping tests presented with lower metabolic demands (V˙ O2 1.42 0.48 and 1.34 0.55 L/min, respectively), ventilatory demands (V˙ O2 45 14 and 43 16 L/min, respectively), and cardiovascular demands (160 20 and 161 19 beats/min, respectively) than the treadmill running test (1.65 0.60 L/min, 54 17 L/min, and 172 7 beats/min, respectively) (P < .05). Between-test agreement in diagnosing EIB was poor (kappa 0.217–0.361). Although EIB prevalence was higher after the treadmill running test (60%) compared to constant (53%) and incremental (47%) stepping tests, 7 subjects developed EIB only in stepping. Clinical and resting functional characteristics did not differ in iscordant subjects (ie, EIB negative in a given test but positive in another) versus concordant subjects (ie, EIB negative or positive in both tests). EIB was not related to individual test ability in eliciting high to very-high ventilation (> 40% or > 60% maximum voluntary ventilation, respectively). Moreover, a negative stepping test but a positive treadmill test (and vice versa) was not associated with greater ventilatory demands. CONCLUSIONS: Lower prevalence of EIB in stepping compared to treadmill running is not related to less ventilation demand in the former modality. Although stepping might be useful as a screening EIB test due its portability and low cost, a negative test should be confirmed with a running-based test in symptomatic children.