Serum laminin in hepatosplenic human schistosomiasis
Serum laminin level was measured in chronic hepatic schistosomiasis. A significant increase in the mean serum laminin levels was observed in patients with hepatosplenic (HS) schistosomiasis (2,57 +/- 0,83 U/ml), as compared to those in patients with the hepatointestinal (HI) form of the disease (1,3...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 1992 |
| País: | Brasil |
| Institución: | Universidade Federal de São Paulo (UNIFESP) |
| Repositorio: | Repositório Institucional da UNIFESP |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.unifesp.br:11600/44894 |
| Acceso en línea: | http://dx.doi.org/10.1590/S0074-02761992000800018 http://repositorio.unifesp.br/handle/11600/44894 |
| Access Level: | acceso abierto |
| Palabra clave: | HUMAN SCHISTOSOMIASIS HEPATOSPLENIC FORM SERUM LAMININ |
| Sumario: | Serum laminin level was measured in chronic hepatic schistosomiasis. A significant increase in the mean serum laminin levels was observed in patients with hepatosplenic (HS) schistosomiasis (2,57 +/- 0,83 U/ml), as compared to those in patients with the hepatointestinal (HI) form of the disease (1,38 +/- 0,45-U/ml) and in the control group (1,15 +/- 0,31 U/ml). In the HS patients there was a significant direct relation between serum laminin and percutaneous splenic pulp pressure (r = 0,68). These findings are compatible with an increased production of laminin in hepatosplenic schistosomiasis with may be related to the observed enlarged liver and spleen basement membranes in such disease. |
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