Comparison between preoperative and intraoperative injection of (99m)Tc Dextran-500 for sentinel lymph node localization in breast cancer

A retrospective study was conducted from a review of the medical records of patients with early-stage, invasive breast cancer who underwent surgical treatment and sentinel node biopsy with a radiotracer from January 2008 to August 2012 at a single institution (221 patients included). The patients we...

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Detalles Bibliográficos
Autores: Gabbi, Maria Cecília Dambros, Masiero, Paulo Ricardo, Uchôa, Diego de Mendonça, Moraes, Ilza Vasques de, Biazús, Jorge Villanova, Edelweiss, Maria Isabel Albano
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:Brasil
Institución:Universidade Federal do Rio Grande do Sul (UFRGS)
Repositorio:Repositório Institucional da UFRGS
Idioma:inglés
OAI Identifier:oai:www.lume.ufrgs.br:10183/143679
Acceso en línea:http://hdl.handle.net/10183/143679
Access Level:acceso abierto
Palabra clave:Biópsia de linfonodo sentinela
Neoplasias da mama
Sentinel lymph node
Breast cancer
99mTc Dextran-500
Intraoperative injection
Preoperative injection
Lymphoscintigraphy
Descripción
Sumario:A retrospective study was conducted from a review of the medical records of patients with early-stage, invasive breast cancer who underwent surgical treatment and sentinel node biopsy with a radiotracer from January 2008 to August 2012 at a single institution (221 patients included). The patients were grouped according to the time of 99mTc Dextran-500 injection, which was preoperatively (with lymphoscintigraphy) (81 patients) or intraoperatively (140 patients). The purpose of the report is to compare the results of sentinel node biopsy of early-stage breast cancer patients who were subjected to intraoperative 99mTc Dextran-500 injections with the patients who received preoperative injections. The following parameters were analyzed: clinical tumor staging, histological and pathological results, size and number of tumor foci, peritumoral vascular invasion, number of lymph nodes removed, size of lymph node metastasis and hormone receptor expression.There were no differences in sentinel lymph node localization whether 99mTc Dextran-500 was injected preoperatively or intraoperatively.