Castleman`s Disease and POEMS Syndrome: case reporte and review of literature

Castleman’s disease is a lymphoproliferative disorder related with human herpesvirus 8 and HIV, presenting in two different ways. The unicentric form is benign, doesn’t have systemic symptoms and is usually cured with surgery. The multicentric form usually presents with generalized lymphadenopathy,...

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Detalhes bibliográficos
Autores: Fontana, Bianca, Zanella, André, Prezzi, Sérgio
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2008
País:Brasil
Recursos:Universidade Federal do Rio Grande do Sul (UFRGS)
Repositório:Clinical and Biomedical Research
Idioma:português
OAI Identifier:oai:seer.ufrgs.br:article/3976
Acesso em linha:https://seer.ufrgs.br/index.php/hcpa/article/view/3976
Access Level:Acceso aberto
Palavra-chave:Doença de Castleman
Síndrome de POEMS
E01.370.374.050
Descrição
Resumo:Castleman’s disease is a lymphoproliferative disorder related with human herpesvirus 8 and HIV, presenting in two different ways. The unicentric form is benign, doesn’t have systemic symptoms and is usually cured with surgery. The multicentric form usually presents with generalized lymphadenopathy, fever, weight loss, and other systemic manifestations and it can be associated with malignancy, especially POEMS syndrome. We report a case of a 50 year old man presenting with weight loss, fever and lymphadenopathy, associated with monoclonal gammopathy, organomegaly, endocrinopathy and neuropathy, which diagnosis was Castleman’s disease with POEMS syndrome