Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans in umbilical cord and peripheral blood, saliva, colostrum from women with gingivitis

This study investigated and compared the presence of Porphyromonas gingivalis (Pg) and Aggregatibacter actinomycetemcomitans (Aa) in biological samples of women submitted to the term delivery diagnosed with gingivitis and healthy periodontium. Oral clinical exams were performed in 48 puerperal women...

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Detalles Bibliográficos
Autores: Curi, Marco Antonio Maluf, Borges, Mariana Castro Loureiro, Geraldo-Martins, Vinicius Rangel, Silva, Camila Beatriz, Rodrigues, Rafael Rocha, Rodrigues, Denise Bertulucci Rocha, Pereira, Sanivia Aparecida Lima, Nogueira, Ruchele Dias
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Brasil
Institución:Universidade Federal de Itajubá (UNIFEI)
Repositorio:Research, Society and Development
Idioma:portugués
OAI Identifier:oai:ojs.pkp.sfu.ca:article/23791
Acceso en línea:https://rsdjournal.org/index.php/rsd/article/view/23791
Access Level:acceso abierto
Palabra clave:Porphyromonas gingivalis
Aggregatibacter actinomycetemcomitans
Sangue do cordão umbilical
Saliva
Colostro.
Cordón umbilical sangre
Colostrum.
Umbilical cord blood
Descripción
Sumario:This study investigated and compared the presence of Porphyromonas gingivalis (Pg) and Aggregatibacter actinomycetemcomitans (Aa) in biological samples of women submitted to the term delivery diagnosed with gingivitis and healthy periodontium. Oral clinical exams were performed in 48 puerperal women including 28 women with healthy periodontium, 15 with gingivitis and 5 with periodontitis (that were excluded of analysis). Samples of umbilical cord blood (CB), peripheral blood (PB), saliva (SA) and colostrum (C) were collected from eligible women after delivery. DNA extraction was accomplished, and the presence of bacteria was detected by PCR with primers and specific probes for each microorganism. Data about previous and current pregnancies and known risk factors were obtained from patients’ medical records. Social, demographic, and oral care data was analyzed by interview. All salivas of participants with gingivitis presented Pg and Aa, while a minority of samples of with healthy periodontium had those bacteria (P<0.05 for each). Sixty percent of the women with gingivitis presented Pg in the blood samples (PB and CB, p<0.05) and 46.6% presented in C. Aa did not present in the blood samples, but 46.6% of women with gingivitis had Aa in the C. No association between socioeconomic and oral health data, detection of microorganisms and presence of the disease. Gingivitis was related to the positive detection of both microorganisms in saliva. Women with gingivitis presented Pg in PB and CB. The presence of Pg and Aa in colostrum occurred only in pregnant women with gingivitis.