Glycogen-rich clear cell carcinoma of the feline mammary gland: Case report

The aim of this report is to describe the first histopathological, immunohistochemical, and clinical characteristics of a feline glycogen-rich clear cell carcinoma (GRCCC). A Persian queen was admitted with mammary gland tumors and underwent radical unilateral mastectomy. Overall survival was consid...

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Detalles Bibliográficos
Autores: Campos, C. B. [UNESP], Gamba, C. O., Damasceno, K. A., Lavalle, G. E., Cassali, G. D.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2016
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/169177
Acceso en línea:http://dx.doi.org/10.1590/1678-4162-8797
http://hdl.handle.net/11449/169177
Access Level:acceso abierto
Palabra clave:Feline
Glycogen-rich clear cell carcinoma
Mammary gland
Neoplasm
Descripción
Sumario:The aim of this report is to describe the first histopathological, immunohistochemical, and clinical characteristics of a feline glycogen-rich clear cell carcinoma (GRCCC). A Persian queen was admitted with mammary gland tumors and underwent radical unilateral mastectomy. Overall survival was considered 33 days and death was due to clinical evolution of the disease. Microscopic evaluation demonstrated epithelial cells arranged in a predominantly solid pattern, tumor cells presented an ample, granular, and foamy clear cytoplasm, and moderate cellular pleomorfism. The presence of cytoplasmatic glycogen was confirmed through diastase digestion followed by PAS staining. Histopathological and histochemical findings lead to the diagnosis of GRCCC with regional metastases.