Synthesis of angiotensin-converting enzyme (ACE) inhibitors: an important class of antihypertensive drugs

ACE inhibitors are one of the most active classes of molecules that lower blood pressure. This report outlines the discovery, the design and development of new compounds, and, structure-activity relationships for this drug category. Updated approaches to planned syntheses of new worthy ACE-inhibitor...

Descripción completa

Detalles Bibliográficos
Autor: Lima, Dênis Pires de
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1999
País:Brasil
Institución:Universidade Federal de Mato Grosso do Sul (UFMS)
Repositorio:Repositório Institucional da UFMS
Idioma:inglés
OAI Identifier:oai:repositorio.ufms.br:123456789/778
Acceso en línea:https://repositorio.ufms.br/handle/123456789/778
http://dx.doi.org/10.1590/S0100-40421999000300016
Access Level:acceso abierto
Palabra clave:Angiotensinas
Anti-Hipertensivos
Inibidores da Enzima Conversora da Angiotensina
Angiotensins
Antihypertensive Agents
Angiotensin-Converting Enzyme Inhibitors
Descripción
Sumario:ACE inhibitors are one of the most active classes of molecules that lower blood pressure. This report outlines the discovery, the design and development of new compounds, and, structure-activity relationships for this drug category. Updated approaches to planned syntheses of new worthy ACE-inhibitors are also exploited.