Incidence of rhegmatogenous retinal detachments after intravitreal antivascular endothelial factor injections

Purpose: To determine the incidence of rhegmatogenous retinal detachments (RD) after intravitreal injection in six high-volume centres.Methods: A consecutive, interventional, multicenter case series measured the incidence of RD in patients receiving intravitreal anti-VEGF. A total of 35 942 intravit...

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Detalles Bibliográficos
Autores: Meyer, Carsten H., Michels, Stephan, Rodrigues, Eduardo B. [UNIFESP], Hager, Annette, Mennel, Stefan, Schmidt, Joerg C., Helb, Hans-Martin, Farah, Michel Eid [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2011
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:inglés
OAI Identifier:oai:repositorio.unifesp.br:11600/33393
Acceso en línea:http://dx.doi.org/10.1111/j.1755-3768.2010.02064.x
http://repositorio.unifesp.br/handle/11600/33393
Access Level:acceso abierto
Palabra clave:adverse events
iatrogenic damage
intravitreal injection
needle
ora serrata
rhegmatogenous retinal detachments
Descripción
Sumario:Purpose: To determine the incidence of rhegmatogenous retinal detachments (RD) after intravitreal injection in six high-volume centres.Methods: A consecutive, interventional, multicenter case series measured the incidence of RD in patients receiving intravitreal anti-VEGF. A total of 35 942 intravitreal anti-VEGF injections (the number of the injections determined by review of injection log books over a 3 year period) were performed under sterile conditions with the patient in a supine position. Injections were given 3.5-4.0 mm behind the limbus in a tunnelled fashion.Results: During 36 consecutive months, five RD were reported, between 2 and 6 days after the injection. of the affected eyes, four were myopic) 1.75 to) -5.5 dpt. the incidence rate of rhegmatogenous RD was 0.013% (5/35 942) per injection.Conclusions: the incidence of RD in our community setting was very low (1 per 7188 injections). All RD occurred during the early postoperative period. the risks of RD can be minimized by a careful injection technique.