Complete nucleotide sequences of two blaKPC-2-Bearing IncN plasmids isolated from sequence Type 442 Klebsiella pneumoniae clinical strains four years apart.
We sequenced the oldest blaKPC-2-bearing plasmid isolated in Brazil and another plasmid also carried by a Klebsiella pneumoniae strain of sequence type 442 (ST442), isolated 52 months later. Both plasmids present an IncN backbone and few acquired regions. Because the 2005 plasmid presented deletions...
| Autores: | , , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2014 |
| País: | Brasil |
| Institución: | Instituto Evandro Chagas (IEC) |
| Repositorio: | Repositório Digital do Instituto Evandro Chagas (Patuá) |
| Idioma: | inglés |
| OAI Identifier: | oai:patua.iec.gov.br:iec/3854 |
| Acceso en línea: | https://patua.iec.gov.br/handle/iec/3854 |
| Access Level: | acceso abierto |
| Palabra clave: | Klebsiella pneumoniae / genética Resistência a Medicamentos / genética Klebsiella pneumoniae / enzimologia beta-lactamases / genética Plasmídeos / genética |
| Sumario: | We sequenced the oldest blaKPC-2-bearing plasmid isolated in Brazil and another plasmid also carried by a Klebsiella pneumoniae strain of sequence type 442 (ST442), isolated 52 months later. Both plasmids present an IncN backbone and few acquired regions. Because the 2005 plasmid presented deletions and a truncated gene within Tn4401b compared to the 2009 plasmid, we can thus infer that IncN blaKPC-2-bearing plasmids pFCF1305 and pFCF3SP had a common ancestor circulating in Brazil prior toMay 2005. |
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