HIGH RATE OF DEPRESSION IN PATIENTS WITH CHRONIC HEPATITIS C

Objectives: To describe the frequency of depression in patients with hepatitis C (HCV) and relate to the biological variables and liver function. Methods: Cross-sectional, descriptive study with a quantitative approach, which assessed depression using the criteria of the Diagnostic and Statistical M...

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Detalles Bibliográficos
Autores: Fakoury, Max Kopti, Ximenes, Catherine da Cal Valdez, Pires, Marcia Amendola, Filho, Aureo Carm, Brito, Alan Messala A., Mello, Carlos Eduardo Brandão
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Brasil
Institución:Universidade Federal do Estado do Rio de Janeiro (UNIRIO)
Repositorio:Revista de Pesquisa: Cuidado é Fundamental Online
Idioma:portugués
OAI Identifier:oai:ojs.seer.unirio.br:article/11384
Acceso en línea:https://seer.unirio.br/cuidadofundamental/article/view/11384
Access Level:acceso abierto
Palabra clave:Chronic Hepatitis C
depression
DSM-V
hepatitis C
Hepatitis C Crónica
depresión
Hepatite C Crônica
depressão
hepatite C
hepatite C crônica
Descripción
Sumario:Objectives: To describe the frequency of depression in patients with hepatitis C (HCV) and relate to the biological variables and liver function. Methods: Cross-sectional, descriptive study with a quantitative approach, which assessed depression using the criteria of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) and the association with biological and liver function variables in 85 patients HCV chronically infected indicated for direct-acting antiviral therapy (DAA) between May 2018 and May 2019. Results: Depression was detected in 47.1% of patients, predominantly mild depression (95%). However, depression occurred independently of biological characteristics, such as gender, age, education, associated comorbidities and liver function, such as degree of fibrosis and viral genotype. Conclusions: The frequency of depression was high in patients with HCV and had no statistical relationship with biological characteristics and liver function, suggesting that active search for depression could be a valuable strategy in managing these patients.