Interrelationship between COVID-19 and diabetes mellitus: a systematic review
Introduction: Individuals with diabetes are at a higher risk of hospitalization and mortality from viral, bacterial and fungal infections. Coronavírus-2019 (COVID-19), caused by severe acute respiratory syndrome coronavírus-2 (SARS-CoV-2), spread rapidly to countries and claimed thousands of lives b...
| Autores: | , , , , , , , |
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| Tipo de documento: | artigo |
| Estado: | Versão publicada |
| Data de publicação: | 2021 |
| País: | Brasil |
| Recursos: | Universidade Federal de Itajubá (UNIFEI) |
| Repositório: | Research, Society and Development |
| Idioma: | português |
| OAI Identifier: | oai:ojs.pkp.sfu.ca:article/12191 |
| Acesso em linha: | https://rsdjournal.org/index.php/rsd/article/view/12191 |
| Access Level: | Acceso aberto |
| Palavra-chave: | COVID-19 Diabetes Coronavirus Mechanisms Infection Systematic review. Mecanismos Infección Revisión sistemática. Coronavírus Infecção Revisão sistemática. |
| Resumo: | Introduction: Individuals with diabetes are at a higher risk of hospitalization and mortality from viral, bacterial and fungal infections. Coronavírus-2019 (COVID-19), caused by severe acute respiratory syndrome coronavírus-2 (SARS-CoV-2), spread rapidly to countries and claimed thousands of lives by December 2020. Notably, in several studies, diabetes is one of the most reported comorbidities in patients with severe COVID-19. Objective: Discuss the influence of diabetes on the prognosis of patients with COVID-19 through a literature review. Methodology: It is a systematic review study. To identify the literature published until December 2020, individual search strategies were applied to the following electronic databases: PubMed, Medline, Lilacs and SciELO. Results: It can be noted that based on the new clinical data obtained from COVID-19 patients, several mechanisms, such as cytokine storm, pulmonary and endothelial dysfunction and hypercoagulation, which can make individuals with diabetes more vulnerable to COVID-19. Epidemiological studies show that poorly controlled diabetes is a risk factor for several infectious diseases. Conclusion: Given the clinical importance of diabetes and the pandemic nature of coronaviruses, understanding how diabetes affects the severity of COVID-19 is critical to the development of public awareness and personalized treatment for individuals affected by the disease. |
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