24-hour urinary sodium excretion and associated factors in non-dialysis chronic kidney disease
This study aims to determine urinary sodium excretion in 24-hour urine and correlate it with associated factors in patients with non-dialysis chronic kidney disease. Methodology: Cross-sectional study with 116 individuals. Demographic, nutritional, clinical and laboratory data were evaluated. Urinar...
| Autores: | , , , , , , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2025 |
| País: | Brasil |
| Recursos: | Universidade Regional do Noroeste do Estado do Rio Grande do Sul (UNIJUI) |
| Repositorio: | Revista Contexto & Saúde (Online) |
| Idioma: | inglés portugués |
| OAI Identifier: | oai:ojs.revistas.unijui.edu.br:article/14297 |
| Acesso em linha: | https://www.revistas.unijui.edu.br/index.php/contextoesaude/article/view/14297 |
| Access Level: | acceso abierto |
| Palavra-chave: | Sódio Eliminação Renal Doença Renal Crônica Taxa de Filtração Glomerular Sodium Renal Elimination Chronic Kidney Disease Glomerular Filtration Rate |
| Resumo: | This study aims to determine urinary sodium excretion in 24-hour urine and correlate it with associated factors in patients with non-dialysis chronic kidney disease. Methodology: Cross-sectional study with 116 individuals. Demographic, nutritional, clinical and laboratory data were evaluated. Urinary sodium excretion was analyzed in 24-hour urine and glomerular filtration rate was estimated using the CKD-EPI equation. Categorical variables were presented as frequencies and percentages, numerical mean ± SD or median. Normality was tested using the Shapiro Wilk test. The median was used to determine urinary sodium excretion in the stages of Chronic Kidney Disease. Pearson's correlation was used to verify the association of the variables with 24-hour urinary sodium excretion. Results: Mean age 51.1 ± 14.0 years, 75.9% female, hypertensive and diabetic 54.3% and 19.8% respectively, 60.9% were in stage one of Chronic Kidney Disease. The median 24-hour urinary sodium excretion by disease stage was higher in stages II 118.6 mmol/L/24h (78.4-155.5) and I 117 mmol/L/24h (96.6-141.0). They correlated positively with 24-hour urinary sodium excretion, body mass index (r = 0.19; p-value 0.004), urinary creatinine (r = 0.48; p-value <0.001), and negatively with age (r = -0.26; p-value 0.006) and total cholesterol (r = -0.20; p-value 0.036). There was a predominance of women, hypertensive patients, stage I chronic kidney disease, elementary school, and income below the minimum wage. Conclusion: Age and total cholesterol were negatively correlated with urinary sodium, while body mass index and urinary creatinine were positively correlated. |
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