Lead, hemoglobin, zinc protoporphyrin and ferritin concentrations in children
OBJECTIVE: To assess the relationship of blood lead and hemoglobin, zinc protoporphyrin, and ferritin concentrations in children. METHODS: A cross-sectional study was carried out in 136 anemic and non-anemic children from two rural villages near a lead smelter in Adrianópolis, Southern Brazil, from...
| Autores: | , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2006 |
| País: | Brasil |
| Recursos: | Universidade de São Paulo (USP) |
| Repositorio: | Revista de Saúde Pública |
| Idioma: | inglés |
| OAI Identifier: | oai:revistas.usp.br:article/31984 |
| Acesso em linha: | https://www.revistas.usp.br/rsp/article/view/31984 |
| Access Level: | acceso abierto |
| Palavra-chave: | Intoxicação por chumbo Anemia Hemoglobina Zinco Protoporfirina Ferritina Estudos transversais Lead Poisoning Hemoglobin Zinc Protoporphyrin Ferritin Cross-sectional studies |
| Resumo: | OBJECTIVE: To assess the relationship of blood lead and hemoglobin, zinc protoporphyrin, and ferritin concentrations in children. METHODS: A cross-sectional study was carried out in 136 anemic and non-anemic children from two rural villages near a lead smelter in Adrianópolis, Southern Brazil, from July to September 2001. Hemoglobin electrophoresis was performed to exclude children with hemoglobin variants and thalassemia syndromes associated with anemia. Lead was determined by atomic absorption spectrophotometry; hemoglobin by automated cell counting; zinc protoporphyrin by hematofluorometry; ferritin by chemiluminescence. Student's t-test, Mann-Whitney test, and the c² test were used to assess the significance of the differences between the variables investigated in anemic and non-anemic children. Stepwise multivariate linear regression analysis was performed using two models for anemic and non-anemic children respectively. RESULTS: Lead was negatively associated to hemoglobin (p |
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