Novel orthohepeviruses in wild rodents from São Paulo State, Brazil
The Hepeviridae comprise single-stranded positive-sense RNA viruses classified into two genera, Orthohepevirus and Piscihepevirus. Orthohepeviruses have a wide host range that includes rodents, but previous studies had been restricted to rodents of the Muridae family. In this study, we applied a hig...
| Autores: | , , , , , , , , |
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| Tipo de documento: | artigo |
| Estado: | Versão publicada |
| Data de publicação: | 2018 |
| País: | Brasil |
| Recursos: | Instituto Evandro Chagas (IEC) |
| Repositório: | Repositório Digital do Instituto Evandro Chagas (Patuá) |
| Idioma: | inglês |
| OAI Identifier: | oai:patua.iec.gov.br:iec/3168 |
| Acesso em linha: | https://patua.iec.gov.br/handle/iec/3168 |
| Access Level: | Acceso aberto |
| Palavra-chave: | Hepatite / diagnóstico Vírus de Hepatite / isolamento & purificação Roedores / virologia Hepatite Viral Humana / virologia |
| Resumo: | The Hepeviridae comprise single-stranded positive-sense RNA viruses classified into two genera, Orthohepevirus and Piscihepevirus. Orthohepeviruses have a wide host range that includes rodents, but previous studies had been restricted to rodents of the Muridae family. In this study, we applied a high-throughput sequencing approach to examine the presence of orthohepeviruses in rodents from São Paulo State, Brazil. We also used RT-PCR to determine the frequency of orthohepeviruses in our sampled population. We identified novel orthohepeviruses in blood samples derived from Necromys lasiurus (1.19%) and Calomys tener (3.66%). Therefore, our results expand the host range and viral diversity of the Hepeviridae family. |
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