Allium cepa bioassay reveals genotoxicity of flumioxazin herbicide
ABSTRACT OBJECTIVE: To analyze the genotoxic potential of an herbicide with flumioxazin using the Allium cepa bioassay. MATERIALS AND METHODS: The herbicide was tested in two concentrations: 0.5 g/L (as indicated for use) and 1.0 g/L (twice the recommended concentration). Distilled...
| Autores: | , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2020 |
| País: | Brasil |
| Institución: | Instituto Evandro Chagas (IEC) |
| Repositorio: | Revista Pan-Amazônica de Saúde (RPAS) |
| Idioma: | portugués |
| OAI Identifier: | oai:revista.iec.gov.br:article/848 |
| Acceso en línea: | https://ojs.iec.gov.br/rpas/article/view/848 |
| Access Level: | acceso abierto |
| Palabra clave: | Genotoxicity Allium cepa Herbicides Mitotic Index Genotoxicidade Herbicidas Índice Mitótico |
| Sumario: | ABSTRACT OBJECTIVE: To analyze the genotoxic potential of an herbicide with flumioxazin using the Allium cepa bioassay. MATERIALS AND METHODS: The herbicide was tested in two concentrations: 0.5 g/L (as indicated for use) and 1.0 g/L (twice the recommended concentration). Distilled water was used as a negative control and 1% sodium benzoate as a positive cytotoxicity control. RESULTS: Toxicity effects were evidenced in both herbicide concentrations. Cytotoxicity effects were observed in the herbicide with flumioxazin at a concentration of 0.5 g/L, which showed a microscopic pattern equal to that of the positive control. The effects of genotoxicity were observed at both concentrations (0.5 g/L and 1.0 g/L) which resulted in chromosomal aberrations in cells, showing that the herbicide directly interferes with the cell cycle of vegetal onion cells. CONCLUSION: The herbicide with flumioxazin showed toxicity and genotoxicity in the analyzed concentrations and effects of cytotoxicity only in the concentration recommended for use. |
|---|