The relationship between post-operative time and cardiac autonomic modulation in breast cancer survivors

Background/objectives: Breast cancer survivors present autonomic dysfunction when evaluated by their heart rate variability (HRV). The purpose of this study is to investigate the relationship between post-operative time and cardiac autonomic modulation in breast cancer survivors and compare these va...

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Autores: Palma, Mariana Romanholi [UNESP], Vanderlei, Luiz Carlos Marques [UNESP], Ribeiro, Fernanda Elisa [UNESP], Mantovani, Alessandra Madia [UNESP], Christofaro, Diego Giulliano Destro [UNESP], Fregonesi, Cristina Elena Prado Teles [UNESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2016
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/173509
Acceso en línea:http://dx.doi.org/10.1016/j.ijcard.2016.09.053
http://hdl.handle.net/11449/173509
Access Level:acceso abierto
Palabra clave:Autonomic nervous system
Breast neoplasms
Heart rate variability
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spelling The relationship between post-operative time and cardiac autonomic modulation in breast cancer survivorsAutonomic nervous systemBreast neoplasmsHeart rate variabilityBackground/objectives: Breast cancer survivors present autonomic dysfunction when evaluated by their heart rate variability (HRV). The purpose of this study is to investigate the relationship between post-operative time and cardiac autonomic modulation in breast cancer survivors and compare these values to those of women without cancer. Methods: This is a cross-sectional study consisting of 45 women from 35 to 70 years old. These women were divided into two after breast cancer groups (BCG1 and BCG2) and a control group (CG). Group BCG1 consisted of women who had undergone breast cancer surgery within the last 18 months and BCG2 those whose postoperative periods were more than 18 months. The control group was formed by cancer-free women. HRV indices were used in the time and the frequency domain and geometric indexes. Results: The indices in millisecond, RMSSD (BCG1 = 19.83; BCG2 = 14.99; CG = 31.46), SD1 (BCG1 = 14.03; BCG2 = 10.61; CG = 22.27), SD2 (BCG1 = 39.17; BCG2 = 35.28; CG = 61.16), SDNN (BCG1 = 29.58; BCG2 = 26.12; CG = 46.36) and HF in milliseconds squared (BCG1 = 194.2; BCG2 = 91.07; CG = 449.4) showed statistically significant reductions in the breast cancer groups compared to the CG (p ≤ 0.0001). Lower SD1 index values were observed when comparing BCG2 to BCG1. Conclusions: Breast cancer survivors regardless of their postoperative period exhibited a decrease in overall variability and both sympathetic and parasympathetic activity when compared to women without the disease. The group with the longer postoperative period manifested more pronounced autonomic modulation changes.Faculty of Science and Technology FCT/UNESPDepartment of Physical Therapy and Graduate Program in Physical Therapy Faculty of Science and Technology FCT/UNESPBiosciences Institute UNESPFaculty of Science and Technology FCT/UNESPDepartment of Physical Therapy and Graduate Program in Physical Therapy Faculty of Science and Technology FCT/UNESPBiosciences Institute UNESPUniversidade Estadual Paulista (Unesp)2018-12-11T17:05:59Z2018-12-11T17:05:59Z2016-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article360-365application/pdfhttp://dx.doi.org/10.1016/j.ijcard.2016.09.053International Journal of Cardiology, v. 224, p. 360-365.1874-17540167-5273http://hdl.handle.net/11449/17350910.1016/j.ijcard.2016.09.0532-s2.0-849884846512-s2.0-84988484651.pdf5860525135106995Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal of Cardiology1,200info:eu-repo/semantics/openAccessPalma, Mariana Romanholi [UNESP]Vanderlei, Luiz Carlos Marques [UNESP]Ribeiro, Fernanda Elisa [UNESP]Mantovani, Alessandra Madia [UNESP]Christofaro, Diego Giulliano Destro [UNESP]Fregonesi, Cristina Elena Prado Teles [UNESP]2024-06-18T18:43:49Zoai:repositorio.unesp.br:11449/173509Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-06-18T18:43:49Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv The relationship between post-operative time and cardiac autonomic modulation in breast cancer survivors
title The relationship between post-operative time and cardiac autonomic modulation in breast cancer survivors
spellingShingle The relationship between post-operative time and cardiac autonomic modulation in breast cancer survivors
Palma, Mariana Romanholi [UNESP]
Autonomic nervous system
Breast neoplasms
Heart rate variability
title_short The relationship between post-operative time and cardiac autonomic modulation in breast cancer survivors
title_full The relationship between post-operative time and cardiac autonomic modulation in breast cancer survivors
title_fullStr The relationship between post-operative time and cardiac autonomic modulation in breast cancer survivors
title_full_unstemmed The relationship between post-operative time and cardiac autonomic modulation in breast cancer survivors
title_sort The relationship between post-operative time and cardiac autonomic modulation in breast cancer survivors
dc.creator.none.fl_str_mv Palma, Mariana Romanholi [UNESP]
Vanderlei, Luiz Carlos Marques [UNESP]
Ribeiro, Fernanda Elisa [UNESP]
Mantovani, Alessandra Madia [UNESP]
Christofaro, Diego Giulliano Destro [UNESP]
Fregonesi, Cristina Elena Prado Teles [UNESP]
author Palma, Mariana Romanholi [UNESP]
author_facet Palma, Mariana Romanholi [UNESP]
Vanderlei, Luiz Carlos Marques [UNESP]
Ribeiro, Fernanda Elisa [UNESP]
Mantovani, Alessandra Madia [UNESP]
Christofaro, Diego Giulliano Destro [UNESP]
Fregonesi, Cristina Elena Prado Teles [UNESP]
author_role author
author2 Vanderlei, Luiz Carlos Marques [UNESP]
Ribeiro, Fernanda Elisa [UNESP]
Mantovani, Alessandra Madia [UNESP]
Christofaro, Diego Giulliano Destro [UNESP]
Fregonesi, Cristina Elena Prado Teles [UNESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.subject.por.fl_str_mv Autonomic nervous system
Breast neoplasms
Heart rate variability
topic Autonomic nervous system
Breast neoplasms
Heart rate variability
description Background/objectives: Breast cancer survivors present autonomic dysfunction when evaluated by their heart rate variability (HRV). The purpose of this study is to investigate the relationship between post-operative time and cardiac autonomic modulation in breast cancer survivors and compare these values to those of women without cancer. Methods: This is a cross-sectional study consisting of 45 women from 35 to 70 years old. These women were divided into two after breast cancer groups (BCG1 and BCG2) and a control group (CG). Group BCG1 consisted of women who had undergone breast cancer surgery within the last 18 months and BCG2 those whose postoperative periods were more than 18 months. The control group was formed by cancer-free women. HRV indices were used in the time and the frequency domain and geometric indexes. Results: The indices in millisecond, RMSSD (BCG1 = 19.83; BCG2 = 14.99; CG = 31.46), SD1 (BCG1 = 14.03; BCG2 = 10.61; CG = 22.27), SD2 (BCG1 = 39.17; BCG2 = 35.28; CG = 61.16), SDNN (BCG1 = 29.58; BCG2 = 26.12; CG = 46.36) and HF in milliseconds squared (BCG1 = 194.2; BCG2 = 91.07; CG = 449.4) showed statistically significant reductions in the breast cancer groups compared to the CG (p ≤ 0.0001). Lower SD1 index values were observed when comparing BCG2 to BCG1. Conclusions: Breast cancer survivors regardless of their postoperative period exhibited a decrease in overall variability and both sympathetic and parasympathetic activity when compared to women without the disease. The group with the longer postoperative period manifested more pronounced autonomic modulation changes.
publishDate 2016
dc.date.none.fl_str_mv 2016-12-01
2018-12-11T17:05:59Z
2018-12-11T17:05:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.ijcard.2016.09.053
International Journal of Cardiology, v. 224, p. 360-365.
1874-1754
0167-5273
http://hdl.handle.net/11449/173509
10.1016/j.ijcard.2016.09.053
2-s2.0-84988484651
2-s2.0-84988484651.pdf
5860525135106995
url http://dx.doi.org/10.1016/j.ijcard.2016.09.053
http://hdl.handle.net/11449/173509
identifier_str_mv International Journal of Cardiology, v. 224, p. 360-365.
1874-1754
0167-5273
10.1016/j.ijcard.2016.09.053
2-s2.0-84988484651
2-s2.0-84988484651.pdf
5860525135106995
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv International Journal of Cardiology
1,200
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 360-365
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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score 15,300719

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