Impact of COVID-19 vaccines on older people: relationship between doses, manufacturers, and mortality

Objective: to analyze the relationship between the number of doses and manufacturers of COVID-19 vaccines and the impact on mortality in older people. Methods: this was an analytical ecological study of people aged 60 and over. The data were obtained from the official Vaccinometer and Coronavirus Da...

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Detalles Bibliográficos
Autores: Silva, Caroline Camilo da, Magno, Gustavo Diego, Uehara, Silvia Carla da Silva André
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:Brasil
Institución:Universidade Federal do Ceará (UFC)
Repositorio:Rev Rene (Online)
Idioma:portugués
inglés
OAI Identifier:oai:periodicos.ufc:article/94780
Acceso en línea:http://periodicos.ufc.br/rene/article/view/94780
Access Level:acceso abierto
Palabra clave:COVID-19; Vacinação; Mortalidade; Idoso.
COVID-19; Vaccination; Mortality; Aged.
Descripción
Sumario:Objective: to analyze the relationship between the number of doses and manufacturers of COVID-19 vaccines and the impact on mortality in older people. Methods: this was an analytical ecological study of people aged 60 and over. The data were obtained from the official Vaccinometer and Coronavirus Dashboard websites and analyzed using descriptive statistics and a generalized linear model with a negative binomial distribution. Results: the COVID-19 mortality coefficient was 498.360/100,000 elderly people before vaccination began and 327.880/100,000 elderly people after vaccination began. Notably, the Janssen vaccine showed a 54.6% reduction in the risk of death in this population group. Conclusion: the analysis of the relationship between the number of doses and manufacturers of COVID-19 vaccines and the impact on mortality showed a positive result, with a significant reduction in the annual mortality rate of the disease among the elderly population after vaccination began. Contributions to practice: the study shows the importance of immunization against COVID-19 in the elderly, highlighting the importance of adherence to booster doses so that this population remains protected.